Michael Addition, substituted methyl (E)-4-oxo-4-phenylbut-2-enoate, pyrimidin-4(3H)-one, substituted (R)-4-oxo-2-(6-oxopyrimidin-1(6H)-yl)-4-phenylbutanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeAza-Michael, Michael Addition alpha-Alkylation, 6,7-dichloro-5-methoxy-2-propyl-2,3-dihydro-1H-inden-1-one, 1,3-dichlorobut-2-ene, (S,Z)-6,7-dichloro-2-(3-chlorobut-2-en-1-yl)-5-methoxy-2-propyl-2,3-dihydro-1H-inden-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]- (9S)-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation Chlorination, substituted tert-butyl (2-(1-substituted-vinyl)phenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, subsituted (S)-4-(chloromethyl)-4-substituted-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, (8α,9R)-9-[2-[bis(2-methylphenyl) amino]benzoate]-cinchonan-9-ol, Cinchonine DerivativeChlorination, Cyclization, Further Cyclizations, Intramolecular cyclization, Lactonization Chloro-O-Cyclization, 2-substituted allyl tosylcarbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, (S,E)-N-(4-substituted-4-(chloromethyl)-1,3-dioxolan-2-ylidene)-4-methylbenzenesulfonamide, (9S)-9-hydroxy-1-[(pentafluorophenyl) methyl]-cinchonanium bromide, Cinchonine DerivativeChlorination, Cyclization, Further Cyclizations, Intramolecular cyclization Epoxidation, 2-substituted naphthalene-1,4-dione, 1a-substituted (1aS,7aR)-1a,7a-dihydronaphtho[2,3-b]oxirene-2,7-dione, 9-hydroxy-6′-methoxy-1-(1-naphthale nylmethyl)-cinchonanium chloride, Cinchonine DerivativeEpoxidation Macrocyclization, 2-substituted 5-(7-(4-fluoro-3-nitrophenyl)alkyl)-phenol, (31Z,33Z)-16-substituted-32-nitro-2-oxa-1(1,3)-benzena-3(1,4)-cyclohexanacyclophane-31,33-diene–ethane (1/1), 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy- (9S)-Cinchonanium bromide (1:1), Cinchonine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization Conjugate Addition, benzyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, (tert-butyl carbonic) 3-((4-methoxybenzyl)oxy)-2-methyl-3-oxopropanoic thioanhydride, (R)-2-((S)-3-(((benzyloxy)carbonyl)amino)-1-methyl-2-oxoindolin-3-yl)-3-((4-methoxybenzyl)oxy)-2-methyl-3-oxopropanoic (tert-butyl carbonic) thioanhydride, N-[3,5-bis(trifluoromethyl)phenyl]- N′-(9R)-cinchonan-9-yl-urea, Cinchonine DerivativeAddition, Mannich, Mannich Aziridination, N-hydroxy-N-phenylpivalamide, tert-butyl acrylate, tert-butyl (S)-1-phenylaziridine-2-carboxylate, (9S)-1-[(3-formyl-2-hydroxy-5-methyl phenyl)methyl]-9-[[(4-methylphenyl) sulfonyl]oxy]-cinchonanium chloride, Cinchonine DerivativeAziridination Epoxidation, (E)-chalcone, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, (9S)-9-hydroxy-1-[(4-iodophenyl) methyl]-cinchonanium bromide, Cinchonine DerivativeEpoxidation Cyclization, tert-butyl (E)-(2-(2-nitrovinyl)phenyl)carbamate, ethyl 4-(2-oxocyclobutane-1-carboxamido)benzoate, tert-butyl (5S,6R)-5-((4-(ethoxycarbonyl)phenyl)carbamoyl)-6-(nitromethyl)-2-oxo-3,4,5,6-tetrahydrobenzo[b]azocine-1(2H)-carboxylate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeCyclization, Cyclization, Further Cyclizations« Older EntriesNext Entries »
Michael Addition, substituted methyl (E)-4-oxo-4-phenylbut-2-enoate, pyrimidin-4(3H)-one, substituted (R)-4-oxo-2-(6-oxopyrimidin-1(6H)-yl)-4-phenylbutanoate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeAza-Michael, Michael Addition
alpha-Alkylation, 6,7-dichloro-5-methoxy-2-propyl-2,3-dihydro-1H-inden-1-one, 1,3-dichlorobut-2-ene, (S,Z)-6,7-dichloro-2-(3-chlorobut-2-en-1-yl)-5-methoxy-2-propyl-2,3-dihydro-1H-inden-1-one, 9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]- (9S)-cinchonanium bromide, Cinchonine DerivativeAlkylation, alpha-Alkylation
Chlorination, substituted tert-butyl (2-(1-substituted-vinyl)phenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, subsituted (S)-4-(chloromethyl)-4-substituted-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, (8α,9R)-9-[2-[bis(2-methylphenyl) amino]benzoate]-cinchonan-9-ol, Cinchonine DerivativeChlorination, Cyclization, Further Cyclizations, Intramolecular cyclization, Lactonization
Chloro-O-Cyclization, 2-substituted allyl tosylcarbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, (S,E)-N-(4-substituted-4-(chloromethyl)-1,3-dioxolan-2-ylidene)-4-methylbenzenesulfonamide, (9S)-9-hydroxy-1-[(pentafluorophenyl) methyl]-cinchonanium bromide, Cinchonine DerivativeChlorination, Cyclization, Further Cyclizations, Intramolecular cyclization
Epoxidation, 2-substituted naphthalene-1,4-dione, 1a-substituted (1aS,7aR)-1a,7a-dihydronaphtho[2,3-b]oxirene-2,7-dione, 9-hydroxy-6′-methoxy-1-(1-naphthale nylmethyl)-cinchonanium chloride, Cinchonine DerivativeEpoxidation
Macrocyclization, 2-substituted 5-(7-(4-fluoro-3-nitrophenyl)alkyl)-phenol, (31Z,33Z)-16-substituted-32-nitro-2-oxa-1(1,3)-benzena-3(1,4)-cyclohexanacyclophane-31,33-diene–ethane (1/1), 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy- (9S)-Cinchonanium bromide (1:1), Cinchonine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization
Conjugate Addition, benzyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, (tert-butyl carbonic) 3-((4-methoxybenzyl)oxy)-2-methyl-3-oxopropanoic thioanhydride, (R)-2-((S)-3-(((benzyloxy)carbonyl)amino)-1-methyl-2-oxoindolin-3-yl)-3-((4-methoxybenzyl)oxy)-2-methyl-3-oxopropanoic (tert-butyl carbonic) thioanhydride, N-[3,5-bis(trifluoromethyl)phenyl]- N′-(9R)-cinchonan-9-yl-urea, Cinchonine DerivativeAddition, Mannich, Mannich
Aziridination, N-hydroxy-N-phenylpivalamide, tert-butyl acrylate, tert-butyl (S)-1-phenylaziridine-2-carboxylate, (9S)-1-[(3-formyl-2-hydroxy-5-methyl phenyl)methyl]-9-[[(4-methylphenyl) sulfonyl]oxy]-cinchonanium chloride, Cinchonine DerivativeAziridination
Epoxidation, (E)-chalcone, phenyl((2S,3R)-3-phenyloxiran-2-yl)methanone, (9S)-9-hydroxy-1-[(4-iodophenyl) methyl]-cinchonanium bromide, Cinchonine DerivativeEpoxidation
Cyclization, tert-butyl (E)-(2-(2-nitrovinyl)phenyl)carbamate, ethyl 4-(2-oxocyclobutane-1-carboxamido)benzoate, tert-butyl (5S,6R)-5-((4-(ethoxycarbonyl)phenyl)carbamoyl)-6-(nitromethyl)-2-oxo-3,4,5,6-tetrahydrobenzo[b]azocine-1(2H)-carboxylate, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]- 4-[(9R)-cinchonan-9-ylamino]-3- cyclobutene-1,2-dione, Cinchonine DerivativeCyclization, Cyclization, Further Cyclizations
