Organocatalyzed Asymmetric Vinylogous Addition of Oxazole-2(3H)-thiones to α, β-Unsaturated Ketones: An Additive-Free Approach for Diversification of Heterocyclic Scaffold.
DOI Number:
10.1021/acs.joc.7b02236
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
4-methyloxazole-2(3H)-thione, (E)-4-phenylbut-3-en-2-one
Product:
(R)-4-(4-methyl-2-thioxo-2,3-dihydrooxazol-5-yl)-4-phenylbutan-2-one
Catalyst:
(9R)-Cinchonan-9-amine
Cas No:
168960-96-1
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5