Fast, highly enantioselective, and sustainable fluorination of 4-substituted pyrazolones catalyzed by amide-based phase-transfer catalysts.

DOI Number:

10.1039/D3QO00269A

Reaction Category:

Educt:

4-substituted pyrazolones, N-fluorbenzolsulfonimid

Product:

2,4,5-trisubstituted 4-fluoro-2,4-dihydro-3H-pyrazol-3-one

Catalyst:

(9S)-1-[2-[[2-(1,1-dimethylethyl)phenyl]amino]-2-oxoethyl]-9-hydroxy-cinchonanium bromide

Cas No:

2798945-97-6

Cas No:

118-10-5