Michael Addition, (E)-3-cyclohexyl-1-phenylprop-2-en-1-one, malonitrile, (R)-2-(1-cyclohexyl-3-oxo-3-phenylpropyl)malononitrile, Quinine BaseMichael, Michael Addition Hydrogenation of alpha-ketoester, ethyl 2-oxopropanoate, hydrogen, ethyl (R)-2-hydroxypropanoate, platinum/aluminiumoxide, Quinine BaseHydrogenation, Hydrogenation of alpha-ketoesters Desymmetrization by Michael Reaction, cyclohexadienones bearing a bisphenylsulfonyl methylene group, polycyclic cyclohexenones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-ylurea, Cinchonine DerivativeDesymmetrization Cascade reaction/Cyclization, beta,gamma-unsaturated amides, beta,gamma-unsaturated alpha-ketoesters, 5,6-dihydropyran-2-ones, 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonine DerivativeCascade reaction, Cyclization, Lactonization Hydrogenation of ketones, 1-(4-substituted-phenyl)ketones, propan-2-ol, 1-(4-substituted-phenyl)alcohols, propan-2-one, (9S)-Cinchonan-9-amine, Cinchonine DerivativeFurther reactions, Hydrogenation, Hydrogenation of ketones Michael Addition, maleimides, aldehydes, 2-(1-substituted-2,5-dioxopyrrolidin-3-yl)-2-substituted-acetaldehyde, (9R)-Cinchonan-9-amine, triphenylphosphine, Cinchonine DerivativeMichael, Michael Addition Michael Addition, unprotected 3-substituted oxindoles, beta-substituted nitroalkenes, 5-substituted-3-substituted-3-(1-nitroalkan-2-yl)indolin-2-one, Diethyl N-(9R)-cinchonan-9-ylphosphoramidate, Cinchonine DerivativeMichael, Michael Addition Trifluoromethylation of aryl ketones, aryl ketones, trimethyl(trifluoromethyl)silane, trifluoromethyl-substituted aryl alcohols, (1S,1’S,2R,2’R,4S,4’S,5R,5’R)-1,1′-(1,3-phenylenebis(methylene))bis(2-((S)-hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium) bromide, tetramethylammonium fluoride, Cinchonine DerivativeTrifluoromethylation Desymmetrization of aziridines with phosphites, (7-azabicyclo[4.1.0]heptan-7-yl)(pyridin-2-yl)methanone (aziridine), diphenyl phosphonate (phosphite), diphenyl ((1R,2R)-2-(picolinamido)cyclohexyl)phosphonate, N-(9R)-Cinchonan-9-yl-2-pyridinecarboxamide, Cinchonine DerivativeDesymmetrization Intramolecular aza-Michael, N-(2-((4′-fluoro-4-oxo-[1,1′-biphenyl]-1(4H)-yl)oxy)ethyl)-4-methylbenzenesulfonamide (cyclohexadienones), (4S,4aS,8aS)-8a-(4-fluorophenyl)-4-tosyl-3,4,4a,8a-tetrahydro-2H-4lambda4-benzo[b][1,4]oxazin-6(5H)-one (morpholine derivative), 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition« Older EntriesNext Entries »
Michael Addition, (E)-3-cyclohexyl-1-phenylprop-2-en-1-one, malonitrile, (R)-2-(1-cyclohexyl-3-oxo-3-phenylpropyl)malononitrile, Quinine BaseMichael, Michael Addition
Hydrogenation of alpha-ketoester, ethyl 2-oxopropanoate, hydrogen, ethyl (R)-2-hydroxypropanoate, platinum/aluminiumoxide, Quinine BaseHydrogenation, Hydrogenation of alpha-ketoesters
Desymmetrization by Michael Reaction, cyclohexadienones bearing a bisphenylsulfonyl methylene group, polycyclic cyclohexenones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-ylurea, Cinchonine DerivativeDesymmetrization
Cascade reaction/Cyclization, beta,gamma-unsaturated amides, beta,gamma-unsaturated alpha-ketoesters, 5,6-dihydropyran-2-ones, 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonine DerivativeCascade reaction, Cyclization, Lactonization
Hydrogenation of ketones, 1-(4-substituted-phenyl)ketones, propan-2-ol, 1-(4-substituted-phenyl)alcohols, propan-2-one, (9S)-Cinchonan-9-amine, Cinchonine DerivativeFurther reactions, Hydrogenation, Hydrogenation of ketones
Michael Addition, maleimides, aldehydes, 2-(1-substituted-2,5-dioxopyrrolidin-3-yl)-2-substituted-acetaldehyde, (9R)-Cinchonan-9-amine, triphenylphosphine, Cinchonine DerivativeMichael, Michael Addition
Michael Addition, unprotected 3-substituted oxindoles, beta-substituted nitroalkenes, 5-substituted-3-substituted-3-(1-nitroalkan-2-yl)indolin-2-one, Diethyl N-(9R)-cinchonan-9-ylphosphoramidate, Cinchonine DerivativeMichael, Michael Addition
Trifluoromethylation of aryl ketones, aryl ketones, trimethyl(trifluoromethyl)silane, trifluoromethyl-substituted aryl alcohols, (1S,1’S,2R,2’R,4S,4’S,5R,5’R)-1,1′-(1,3-phenylenebis(methylene))bis(2-((S)-hydroxy(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium) bromide, tetramethylammonium fluoride, Cinchonine DerivativeTrifluoromethylation
Desymmetrization of aziridines with phosphites, (7-azabicyclo[4.1.0]heptan-7-yl)(pyridin-2-yl)methanone (aziridine), diphenyl phosphonate (phosphite), diphenyl ((1R,2R)-2-(picolinamido)cyclohexyl)phosphonate, N-(9R)-Cinchonan-9-yl-2-pyridinecarboxamide, Cinchonine DerivativeDesymmetrization
Intramolecular aza-Michael, N-(2-((4′-fluoro-4-oxo-[1,1′-biphenyl]-1(4H)-yl)oxy)ethyl)-4-methylbenzenesulfonamide (cyclohexadienones), (4S,4aS,8aS)-8a-(4-fluorophenyl)-4-tosyl-3,4,4a,8a-tetrahydro-2H-4lambda4-benzo[b][1,4]oxazin-6(5H)-one (morpholine derivative), 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
