Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins.
DOI Number:
10.1039/C1SC00390A
Reaction Category:
Educt:
unprotected 3-substituted oxindoles, beta-substituted nitroalkenes
Product:
5-substituted-3-substituted-3-(1-nitroalkan-2-yl)indolin-2-one
Catalyst:
Diethyl N-(9R)-cinchonan-9-ylphosphoramidate
Cas No:
1354565-16-4
Associated Product from Buchler GmbH:
Cinchonine Base
Cas No:
118-10-5