Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins.

DOI Number:

10.1039/C1SC00390A

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

unprotected 3-substituted oxindoles, beta-substituted nitroalkenes

Product:

5-substituted-3-substituted-3-(1-nitroalkan-2-yl)indolin-2-one

Catalyst:

Diethyl N-(9R)-cinchonan-9-ylphosphoramidate

Cas No:

1354565-16-4

Cas No:

118-10-5