Domino Michael cyclization, 2-mercaptobenzaldehyde, (E)-3-(3-substituted-acryloyl)oxazolidin-2-one, 3-((2S,3S,4R)-2-substituted-4-hydroxythiochromane-3-carbonyl)oxazolidin-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Aldol, Cyclization, Cyclization, Michael, Michael Addition, Sulfa-Michael Addition Mannich reaction, N/C-substituted-3-fluoroindolin-2-one, N/C-substituted-3-iminoindolin-2-one, N/C-substituted-(3R,3’S)-3-amino-3′-fluoro-[3,3′-biindoline]-2,2′-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Hydrogenation, (Z)-2-substituted-3-(4-ethersubstituted-phenyl)acrylic acid, dihydrogen, (R)-2-substituted-3-(4-ethersubstituted-phenyl)propanoic acid, palladium/carbon, Cinchonidine BaseHydrogenation 1,2 Addition Michael addition, (E)-1-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)-2-phenylethane-1,2-dione, diethylzinc, (2R,3R)-2-ethoxy-3-(2-oxo-2-phenylethyl)-2-phenyl-2,3-dihydro-1H-inden-1-one, Cinchonidine BaseAddition, Cascade reaction, Michael, Michael Addition Hydrogenation of alpha-Ketoeste, methyl 2-(4-halogenophenyl)-2-oxoacetate, methyl (S)-2-(4-halogenophenyl)-2-hydroxyacetate, platinum/aluminiumoxide, Dihydrocinchonidine BaseHydrogenation, Hydrogenation of alpha-ketoesters Trifluoromethylthiolation, 2-(phenylthio)-2,3-dihydro-1H-inden-1-one, 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione, (R)-2-(phenylthio)-2-((trifluoromethyl)thio)-2,3-dihydro-1H-inden-1-one, Dihydroquinine BaseTrifluoro-methylthiolation Sulfenylation, 3-((4-chlorophenyl)thio)-5-methoxyindolin-2-one, 1-(phenylthio)pyrrolidine-2,5-dione, (S)-3-((4-chlorophenyl)thio)-5-methoxy-3-(phenylthio)indolin-2-one, Dihydroquinine BaseSulfenylation 1,3 dipolar cycloaddition cascade, methyl-2-oxo-2H-pyran-3-carboxylate, (E)-1-methyl-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, methyl (3S,3’R,3a’S,5a’S,6’R,8’R,8a’R,8b’S)-1,1”-dimethyl-2,2”,5′-trioxo-3′,8′-bis(trifluoromethyl)-3′,3a’,7′,8′,8a’,8b’-hexahydro-2’H-dispiro[indoline-3,1′-pyrano[2,3-c:4,5-c’]dipyrrole-6′,3”-indoline]-5a'(5’H)-carboxylate, Dihydroquinine Base1,3-Dipolar Cycloaddition, Cascade reaction, Cycloaddition Mannich reaction, 2-chlorobenzaldehyde, 4,5,6,7-tetrahydrothieno[3,2-c]pyridine, trimethylsilanecarbonitrile, (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile, Dihydroquinine BaseMannich, Mannich α-selenation of Azlactones, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, 2-(phenylselanyl)isoindoline-1,3-dione, 4-(2-(methylthio)ethyl)-2-phenyl-4-(phenylselanyl)oxazol-5(4H)-one, Dihydroquinine BaseSelenation« Older EntriesNext Entries »
Domino Michael cyclization, 2-mercaptobenzaldehyde, (E)-3-(3-substituted-acryloyl)oxazolidin-2-one, 3-((2S,3S,4R)-2-substituted-4-hydroxythiochromane-3-carbonyl)oxazolidin-2-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Aldol, Cyclization, Cyclization, Michael, Michael Addition, Sulfa-Michael Addition
Mannich reaction, N/C-substituted-3-fluoroindolin-2-one, N/C-substituted-3-iminoindolin-2-one, N/C-substituted-(3R,3’S)-3-amino-3′-fluoro-[3,3′-biindoline]-2,2′-dione, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Hydrogenation, (Z)-2-substituted-3-(4-ethersubstituted-phenyl)acrylic acid, dihydrogen, (R)-2-substituted-3-(4-ethersubstituted-phenyl)propanoic acid, palladium/carbon, Cinchonidine BaseHydrogenation
1,2 Addition Michael addition, (E)-1-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)-2-phenylethane-1,2-dione, diethylzinc, (2R,3R)-2-ethoxy-3-(2-oxo-2-phenylethyl)-2-phenyl-2,3-dihydro-1H-inden-1-one, Cinchonidine BaseAddition, Cascade reaction, Michael, Michael Addition
Hydrogenation of alpha-Ketoeste, methyl 2-(4-halogenophenyl)-2-oxoacetate, methyl (S)-2-(4-halogenophenyl)-2-hydroxyacetate, platinum/aluminiumoxide, Dihydrocinchonidine BaseHydrogenation, Hydrogenation of alpha-ketoesters
Trifluoromethylthiolation, 2-(phenylthio)-2,3-dihydro-1H-inden-1-one, 1-((trifluoromethyl)thio)pyrrolidine-2,5-dione, (R)-2-(phenylthio)-2-((trifluoromethyl)thio)-2,3-dihydro-1H-inden-1-one, Dihydroquinine BaseTrifluoro-methylthiolation
Sulfenylation, 3-((4-chlorophenyl)thio)-5-methoxyindolin-2-one, 1-(phenylthio)pyrrolidine-2,5-dione, (S)-3-((4-chlorophenyl)thio)-5-methoxy-3-(phenylthio)indolin-2-one, Dihydroquinine BaseSulfenylation
1,3 dipolar cycloaddition cascade, methyl-2-oxo-2H-pyran-3-carboxylate, (E)-1-methyl-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, methyl (3S,3’R,3a’S,5a’S,6’R,8’R,8a’R,8b’S)-1,1”-dimethyl-2,2”,5′-trioxo-3′,8′-bis(trifluoromethyl)-3′,3a’,7′,8′,8a’,8b’-hexahydro-2’H-dispiro[indoline-3,1′-pyrano[2,3-c:4,5-c’]dipyrrole-6′,3”-indoline]-5a'(5’H)-carboxylate, Dihydroquinine Base1,3-Dipolar Cycloaddition, Cascade reaction, Cycloaddition
Mannich reaction, 2-chlorobenzaldehyde, 4,5,6,7-tetrahydrothieno[3,2-c]pyridine, trimethylsilanecarbonitrile, (S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile, Dihydroquinine BaseMannich, Mannich
α-selenation of Azlactones, 4-(2-(methylthio)ethyl)-2-phenyloxazol-5(4H)-one, 2-(phenylselanyl)isoindoline-1,3-dione, 4-(2-(methylthio)ethyl)-2-phenyl-4-(phenylselanyl)oxazol-5(4H)-one, Dihydroquinine BaseSelenation
