Asymmetric Synthesis of Tricycle‐Fused Dispirooxindoles via Organocatalyzed Three‐Component Cascade Reactions of 2‐Pyrones and Trifluoroethylisatin Ketimines.
DOI Number:
10.1002/adsc.202200846
Reaction Category:
RXNO ID:
RXNO_0000018
Educt:
methyl-2-oxo-2H-pyran-3-carboxylate, (E)-1-methyl-3-((2,2,2-trifluoroethyl)imino)indolin-2-one
Product:
methyl-(3S,3'R,3a'S,5a'S,6'R,8'R,8a'R,8b'S)-1,1''-dimethyl-2,2'',5'-trioxo-3',8'-bis(trifluoromethyl)-3',3a',7',8',8a',8b'-hexahydro-2'H-dispiro[indoline-3,1'-pyrano[2,3-c:4,5-c']dipyrrole-6',3''-indoline]-5a'(5'H)-carboxylate
Catalyst:
Dihydroquinine Base
Cas No:
522-66-7
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7