Modified asymmetric Strecker reaction of aldehyde with secondary amine: A protocol for the synthesis of S-clopidogrel (an antiplatelet agent). 

DOI Number:

10.1021/jo300642z

Reaction Category:

Educt:

2-chlorobenzaldehyde, 4,5,6,7-tetrahydrothieno[3,2-c]pyridine, trimethylsilanecarbonitrile

Product:

(S)-2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetonitrile

Catalyst:

Dihydroquinine Base

Cas No:

522-66-7

Cas No:

522-66-7