Umpolung Chemo-and Regioselective Cascade Addition of Diethylzinc to α-Diketones Followed by Intramolecular Michael Reaction: Stereoselective Synthesis of Highly Substituted 1-Indanones.
DOI Number:
10.1021/acs.orglett.2c02539
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
(E)-1-(2-(3-oxo-3-phenylprop-1-en-1-yl)phenyl)-2-phenylethane-1,2-dione, diethylzinc
Product:
(2R,3R)-2-ethoxy-3-(2-oxo-2-phenylethyl)-2-phenyl-2,3-dihydro-1H-inden-1-one
Catalyst:
Cinchonidine Base
Cas No:
485-71-2
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2