Alkylation, o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 3-bromoprop-1-ene, (bromomethyl)benzene, substituited o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide, Dihydrocinchonidine DerivativeAlkylation, Alkylation Aziridination, 1-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazol-1-yl)prop-2-en-1-one, N-chloro-N-sodiocarbamates, benzyl (S)-2-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole-1-carbonyl)aziridine-1-carboxylate, 1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeAziridination Spirocyclization, substituted cyclopent-2-en-1-one, substituted isoxazol-5(4H)-one, aldehydes, substituted tetrahydro-4’H,5H-spiro[isoxazole-4,2′-pentalene]-4′,5-dione, 4-methylsalicylic acid, (8α,9S)-2′-(1,1-Dimethylethyl)cinchonan-9-amine, Cinchonidine DerivativeSpirocyclization Iodination, substituted (1Z,3E)-hexa-3,5-dienal oxime, N-Iodsuccinimid, substituted (R,E)-5-(3-iodoprop-1-en-1-yl)-4,5-dihydroisoxazole, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11- dihydro-11-phenylcinchonan-9-yl]-thiourea, Cinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization Chlorocyclization, substituted o-vinylanilide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted chloromethyl-2-phenyl-4H-benzoxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization α-Hydroxylation, β‐dicarbonyl compounds, 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylic acid ester, tetraphenylporphyrin, 1-[(3,5-dibromophenyl)methyl]-9-hydroxy-2′-(2-naphthalenyl)-(9S)-cinchonanium bromide, Cinchonine DerivativeHydroxylation Assymetric Arylation, substituted 2-oxocyclopentane-1-carboxylic acid ester, substituted 1-fluoro-2-nitrobenzene, substituted 1-(2-nitrophenyl)-2-oxocyclopentane-1-carboxylic acid ester, 9-(benzoyloxy)-1-(phenylmethyl)-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeArylation, Further reactions conjugate addition, isatin derived N-Cbz ketimines, monothiomalonates, chiral 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeAddition Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylation Spirocyclization, dioxindoles, trans-α-cyano-α,β-unsaturated ketones, dihydrofuran-spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization« Older EntriesNext Entries »
Alkylation, o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 3-bromoprop-1-ene, (bromomethyl)benzene, substituited o-biphenyl-2-oxazoline-4-carboxylic acid tert-butyl ester, 1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide, Dihydrocinchonidine DerivativeAlkylation, Alkylation
Aziridination, 1-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazol-1-yl)prop-2-en-1-one, N-chloro-N-sodiocarbamates, benzyl (S)-2-((4R,7S)-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole-1-carbonyl)aziridine-1-carboxylate, 1-(9-anthracenylmethyl)-9-(2-propenyloxy)-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeAziridination
Spirocyclization, substituted cyclopent-2-en-1-one, substituted isoxazol-5(4H)-one, aldehydes, substituted tetrahydro-4’H,5H-spiro[isoxazole-4,2′-pentalene]-4′,5-dione, 4-methylsalicylic acid, (8α,9S)-2′-(1,1-Dimethylethyl)cinchonan-9-amine, Cinchonidine DerivativeSpirocyclization
Iodination, substituted (1Z,3E)-hexa-3,5-dienal oxime, N-Iodsuccinimid, substituted (R,E)-5-(3-iodoprop-1-en-1-yl)-4,5-dihydroisoxazole, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11- dihydro-11-phenylcinchonan-9-yl]-thiourea, Cinchonidine DerivativeCyclization, Iodination, Iodoetherification, Isoxazoline cyclization
Chlorocyclization, substituted o-vinylanilide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted chloromethyl-2-phenyl-4H-benzoxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization
α-Hydroxylation, β‐dicarbonyl compounds, 2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylic acid ester, tetraphenylporphyrin, 1-[(3,5-dibromophenyl)methyl]-9-hydroxy-2′-(2-naphthalenyl)-(9S)-cinchonanium bromide, Cinchonine DerivativeHydroxylation
Assymetric Arylation, substituted 2-oxocyclopentane-1-carboxylic acid ester, substituted 1-fluoro-2-nitrobenzene, substituted 1-(2-nitrophenyl)-2-oxocyclopentane-1-carboxylic acid ester, 9-(benzoyloxy)-1-(phenylmethyl)-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeArylation, Further reactions
conjugate addition, isatin derived N-Cbz ketimines, monothiomalonates, chiral 3-substituted 3-amino-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylurea, Cinchonidine DerivativeAddition
Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylation
Spirocyclization, dioxindoles, trans-α-cyano-α,β-unsaturated ketones, dihydrofuran-spirooxindoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeSpirocyclization
