Asymmetric [5+ 3] formal cycloadditions with cyclic enones through cascade dienamine–dienamine catalysis.

DOI Number:

10.1002/ange.201403753
Link to literature

Reaction Category:

Spirocyclization

Educt:

cyclic enones, substituted 3-vinylbenzo[d]isothiazole 1,1-dioxide

Product:

substituted (3R,3a'S,6a'S)-2',3',3a',6a'-tetrahydro-2H,4'H-spiro[benzo[d]isothiazole-3,1'-pentalen]-4'-one 1,1-dioxide

Catalyst:

5-Nitrosalicylic acid, (8α,9R)-6′-Methoxycinchonan-9-amine

Cas No:

189309-10-2

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0