Sulfa-Michael addition, 3-methylbenzenethiol, ethyl (Z)-2-fluoro-5-phenylpent-2-enoate, ethyl (2S,3S)-2-fluoro-5-phenyl-3-(m-tolylthio)pentanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Cascade reaction, diethyl 2-bromomalonate, 4-arylidenepyrazol-5-ones, spirocyclopropylpyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCascade reaction, Spirocyclization Ugi-type reaction, α-aryl-substituted isocyanoacetates, C,N-cyclic azomethine imines, C1-oxazole-substituted tetrahydroisoquinolines, 3-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFurther reactions, Ugi-type reaction Mannich reaction, α-isocyanoacetates, N-(2-benzothiazolyl)imines, benzothiazole-dihydroimidazoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMannich, Mannich Aza-Michael Addition, tert-butyl (E)-(2-((4-oxopent-2-en-1-yl)oxy)ethyl)carbamate, tert-butyl (S)-3-(2-oxopropyl)morpholine-4-carboxylate, diphenyl hydrogenphosphate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition Aza-Michael Addition, benzyl (E)-((6-oxohept-4-en-1-yl)oxy)carbamate, benzyl (R)-3-(2-oxopropyl)-1,2-oxazinane-2-carboxylate, pentafluoropropionic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition Aza-Michael Addition, 4-nitrophthalimide, α,β-unsaturated ketones, 2-(1-substituted-3-oxo-3-substitutedpropyl)-5-nitroisoindoline-1,3-diones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition Cascade reaction, (E)-N-(4-bromo-2-(3-oxo-3-phenylprop-1-en-1-yl)phenethyl)-2-chloroacetamide, (1R,10bR)-1-benzoyl-9-bromo-1,5,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-3(2H)-one, (8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-Cinchonanium chloride (1:2), Cinchonidine DerivativeCascade reaction Cascade reaction, 2-aminophenol, ethyl (E)-3-(2-((E)-2-nitroprop-1-en-1-yl)phenoxy)acrylate, ethyl 2-((2S,3R,4S)-4-((2-hydroxyphenyl)amino)-3-methyl-3-nitrochroman-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Cascade reaction, 4-cyanobenzaldehyde, 2-(phenylsulfonyl)acetonitrile, benzathine, (R)-4-(1,4-dibenzyl-3-oxopiperazin-2-yl)benzonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction« Older EntriesNext Entries »
Sulfa-Michael addition, 3-methylbenzenethiol, ethyl (Z)-2-fluoro-5-phenylpent-2-enoate, ethyl (2S,3S)-2-fluoro-5-phenyl-3-(m-tolylthio)pentanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Cascade reaction, diethyl 2-bromomalonate, 4-arylidenepyrazol-5-ones, spirocyclopropylpyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Ugi-type reaction, α-aryl-substituted isocyanoacetates, C,N-cyclic azomethine imines, C1-oxazole-substituted tetrahydroisoquinolines, 3-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFurther reactions, Ugi-type reaction
Mannich reaction, α-isocyanoacetates, N-(2-benzothiazolyl)imines, benzothiazole-dihydroimidazoles, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeMannich, Mannich
Aza-Michael Addition, tert-butyl (E)-(2-((4-oxopent-2-en-1-yl)oxy)ethyl)carbamate, tert-butyl (S)-3-(2-oxopropyl)morpholine-4-carboxylate, diphenyl hydrogenphosphate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
Aza-Michael Addition, benzyl (E)-((6-oxohept-4-en-1-yl)oxy)carbamate, benzyl (R)-3-(2-oxopropyl)-1,2-oxazinane-2-carboxylate, pentafluoropropionic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
Aza-Michael Addition, 4-nitrophthalimide, α,β-unsaturated ketones, 2-(1-substituted-3-oxo-3-substitutedpropyl)-5-nitroisoindoline-1,3-diones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Michael Addition
Cascade reaction, (E)-N-(4-bromo-2-(3-oxo-3-phenylprop-1-en-1-yl)phenethyl)-2-chloroacetamide, (1R,10bR)-1-benzoyl-9-bromo-1,5,6,10b-tetrahydropyrrolo[2,1-a]isoquinolin-3(2H)-one, (8α,9R)-(8′′α,9′′R)-1,1′′-[9,10-anthracenediylbis(methylene)]bis[9-hydroxy-Cinchonanium chloride (1:2), Cinchonidine DerivativeCascade reaction
Cascade reaction, 2-aminophenol, ethyl (E)-3-(2-((E)-2-nitroprop-1-en-1-yl)phenoxy)acrylate, ethyl 2-((2S,3R,4S)-4-((2-hydroxyphenyl)amino)-3-methyl-3-nitrochroman-2-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Cascade reaction, 4-cyanobenzaldehyde, 2-(phenylsulfonyl)acetonitrile, benzathine, (R)-4-(1,4-dibenzyl-3-oxopiperazin-2-yl)benzonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine DerivativeCascade reaction
