Streocontrolled construction of six vicinal stereogenic centers on spiropyrazolones via organocascade Michael/Michael/1, 2-addition reactions.
DOI Number:
10.1021/ol501093v
Reaction Category:
Educt:
ethyl 3-oxobutanoate, (E)-(2-nitrovinyl)benzene, (Z)-4-benzylidene-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one
Product:
spiropyrazolones
Catalyst:
3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1210360-60-3
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0