Organocatalytic Biomimetic Decarboxylative Aldol Reaction of Fluorinated β‐Keto Acids with Unprotected Isatins.

DOI Number:

10.1002/adsc.201800831

Reaction Category:

Educt:

4-fluoroisatin, 3-(4-chlorophenyl)-2,2-difluoro-3-oxopropanoic acid

Product:

(S)-3-(2-(4-chlorophenyl)-1,1-difluoro-2-oxoethyl)-4-fluoro-3-hydroxyindolin-2-one

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea

Cas No:

957770-66-0

Cas No:

130-95-0