Organocatalytic Biomimetic Decarboxylative Aldol Reaction of Fluorinated β‐Keto Acids with Unprotected Isatins.
DOI Number:
10.1002/adsc.201800831
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
4-fluoroisatin, 3-(4-chlorophenyl)-2,2-difluoro-3-oxopropanoic acid
Product:
(S)-3-(2-(4-chlorophenyl)-1,1-difluoro-2-oxoethyl)-4-fluoro-3-hydroxyindolin-2-one
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea
Cas No:
957770-66-0
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0