[2+2]-Cycloaddition, acid chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzolyquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition Vinylogous Michael Addition, 3-ethylcyclohex-2-en-1-one, N-(2-tert-Butylphenyl)maleimide, (R)-1-(2-(tert-butyl)phenyl)-3-((R)-1-(3-oxocyclohex-1-en-1-yl)ethyl)pyrrolidine-2,5-dione, N-Boc-L-phenylglycine, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Michael Addition, Vinylogous Michael Addition Diels-Alder Desymmetrization, N-(2-tert-butylphenyl)maleimide, (E)-4-phenylbut-3-en-2-one, (3aR,7S,7aS)-2-(2-(tert-butyl)phenyl)-7-phenyltetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Cycloaddition, Desymmetrization, Diels-Alder reaction N,N-Atropisomer synthesis, 2-phenylpropanal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, (bromomethyl)benzene, di-tert-butyl (S)-1-benzyl-2-(1-oxo-2-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, (8α,9S)-6′-Methoxycinchonan-9-amine, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAtropisomer synthesis Aza-Michael Addition, benzyl (E)-(7-oxooct-5-en-1-yl)carbamate, benzyl (R)-2-(2-oxopropyl)piperidine-1-carboxylate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition Dihydroxylation, methyl (E)-4-(2-iodo-6-methylphenyl)but-2-enoate, methyl (2R,3S)-2,3-dihydroxy-4-(2-iodo-6-methylphenyl)butanoate, Dipotassium osmate, (8α,9R)-10,11-dihydro-6′-methoxy-9-(9-phenanthrenyloxy)-Cinchonan, Dihydroquinine DerivativeDihydroxylation, Further reactions, Hydroxylation Aza-Friedel-Crafts reaction, tert-butyl (E)-(1-benzyl-2-oxoindolin-3-ylidene)carbamates, naphthols, tert-butyl (R)-(1-benzyl-3-(1-hydroxynaphthalen-2-yl)-2-oxoindolin-3-yl)carbamates, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Thiourea (aminoalkyl polystyrene resin-supported), Dihydroquinine DerivativeAza-Friedel-Crafts, Friedel-Crafts Sulfa-Michael addition, 3-methylbenzenethiol, ethyl (Z)-2-fluoro-5-phenylpent-2-enoate, ethyl (2S,3S)-2-fluoro-5-phenyl-3-(m-tolylthio)pentanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition Cascade reaction, diethyl 2-bromomalonate, 4-arylidenepyrazol-5-ones, spirocyclopropylpyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCascade reaction, Spirocyclization Ugi-type reaction, α-aryl-substituted isocyanoacetates, C,N-cyclic azomethine imines, C1-oxazole-substituted tetrahydroisoquinolines, 3-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFurther reactions, Ugi-type reaction« Older EntriesNext Entries »
[2+2]-Cycloaddition, acid chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzolyquinine, Quinine Derivative[2+2]-Cycloaddition, Cycloaddition
Vinylogous Michael Addition, 3-ethylcyclohex-2-en-1-one, N-(2-tert-Butylphenyl)maleimide, (R)-1-(2-(tert-butyl)phenyl)-3-((R)-1-(3-oxocyclohex-1-en-1-yl)ethyl)pyrrolidine-2,5-dione, N-Boc-L-phenylglycine, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Michael Addition, Vinylogous Michael Addition
Diels-Alder Desymmetrization, N-(2-tert-butylphenyl)maleimide, (E)-4-phenylbut-3-en-2-one, (3aR,7S,7aS)-2-(2-(tert-butyl)phenyl)-7-phenyltetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAtropisomer synthesis, Cycloaddition, Desymmetrization, Diels-Alder reaction
N,N-Atropisomer synthesis, 2-phenylpropanal, di-tert-butyl (E)-diazene-1,2-dicarboxylate, (bromomethyl)benzene, di-tert-butyl (S)-1-benzyl-2-(1-oxo-2-phenylpropan-2-yl)hydrazine-1,2-dicarboxylate, (8α,9S)-6′-Methoxycinchonan-9-amine, (8α,9R)-9-hydroxy-6′-methoxy-1-(phenylmethyl)-Cinchonanium bromide, Quinine DerivativeAtropisomer synthesis
Aza-Michael Addition, benzyl (E)-(7-oxooct-5-en-1-yl)carbamate, benzyl (R)-2-(2-oxopropyl)piperidine-1-carboxylate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine DerivativeAza-Michael, Intramolecular Aza-Michael, Michael Addition
Dihydroxylation, methyl (E)-4-(2-iodo-6-methylphenyl)but-2-enoate, methyl (2R,3S)-2,3-dihydroxy-4-(2-iodo-6-methylphenyl)butanoate, Dipotassium osmate, (8α,9R)-10,11-dihydro-6′-methoxy-9-(9-phenanthrenyloxy)-Cinchonan, Dihydroquinine DerivativeDihydroxylation, Further reactions, Hydroxylation
Aza-Friedel-Crafts reaction, tert-butyl (E)-(1-benzyl-2-oxoindolin-3-ylidene)carbamates, naphthols, tert-butyl (R)-(1-benzyl-3-(1-hydroxynaphthalen-2-yl)-2-oxoindolin-3-yl)carbamates, N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-Thiourea (aminoalkyl polystyrene resin-supported), Dihydroquinine DerivativeAza-Friedel-Crafts, Friedel-Crafts
Sulfa-Michael addition, 3-methylbenzenethiol, ethyl (Z)-2-fluoro-5-phenylpent-2-enoate, ethyl (2S,3S)-2-fluoro-5-phenyl-3-(m-tolylthio)pentanoate, (8α,9R)-(8′′α,9′′R)-9,9′′-[(2,5-Diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
Cascade reaction, diethyl 2-bromomalonate, 4-arylidenepyrazol-5-ones, spirocyclopropylpyrazolones, 1,4-bis[[(8α,9R)-10,11-dihydro-6′-methoxy-cinchonan-9-yl]oxy]-9,10-Anthracenedione, Dihydroquinine DerivativeCascade reaction, Spirocyclization
Ugi-type reaction, α-aryl-substituted isocyanoacetates, C,N-cyclic azomethine imines, C1-oxazole-substituted tetrahydroisoquinolines, 3-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFurther reactions, Ugi-type reaction
