Enantioselective construction of quaternary stereocenters via organocatalytic arylation of isoxazolin-5-ones with o-quinone diimides.

DOI Number:

10.1039/D3QO01600E
Link to literature

Reaction Category:

Arylation | Further reactions

Educt:

4-(3-methoxybenzyl)-3-methylisoxazol-5(4H)-one, N,N'-((1E,2Z)-cyclohexa-3,5-diene-1,2-diylidene)dibenzamide

Product:

(R)-N,N'-(4-(4-(3-methoxybenzyl)-3-methyl-5-oxo-4,5-dihydroisoxazol-4-yl)-1,2-phenylene)dibenzamide

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-86-9

Associated Product from Buchler GmbH:

Cinchonidine Base

Cas No:

485-71-2