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Mannich reaction, imines, sulfonylacetonitriles, β-amino nitriles, 9H-Fluoren-9-ylmethyl N-[(1S)-1-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]carbonyl]amino]-2,2-dimethylpropyl]carbamate, Quinine Derivative

Mannich, Mannich

Sulfa-Michael Addition, aromatic thiols, nitroalkenes, 2-nitro-1-arylethyl sulfides, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine Derivative

Michael Addition, Sulfa-Michael, Sulfa-Michael Addition

[4+2]-Annulation, 3-nitroindoles, Nazarov reagents, hydrocarbazoles, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzenepropanamide, Quinine Derivative

[4+2] Annulation, Cyclization, Further Cyclizations

Michael Addition, 3-substituted phthalides, nitroolefins, 3,3-disubstituted phthalide derivatives, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine Derivative

Michael, Michael Addition

Cyclopropanation, oxindoles, bromonitroolefins, 3-spirocyclopropyl-2-oxindoles, (2S)-2-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-3,3-dimethylbutanamide, Quinine Derivative

Cyclopropanation, Spirocyclization

[3+1]-Annulation, 3-chloro-1-methylindolin-2-one, benzoyl(3,4-dihydroisoquinolin-2-ium-2-yl)amide, (3S,3aR,8aS)-2-benzoyl-1′-methyl-1,3a,8,8a-tetrahydro-2H-spiro[indeno[2,1-c]pyrazole-3,3′-indolin]-2′-one, 6-Chloro-1-hydroxybenzotriazole, N-[(1R,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative

[3+1]-Annulation, Cyclization, Further Cyclizations

[4+2]-Cycloaddition, α,β-unsaturated aldehydes, nitroalkenes, acetic anhydride, subsituted cyclohexenes, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(8α,9R)-6′-methoxycinchonan-9-yl]-thiourea, Quinine Derivative

[4+2]-Cycloaddition, Cycloaddition

Cyanoethoxycarbonylation, isatins, ethyl carbonocyanidate, substituted (R)-3-cyano-2-oxoindolin-3-yl ethyl carbonate, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-3,5-bis(trifluoromethyl)-benzenesulfonamide linked to MCM-41, Quinine Derivative

Cyanoethoxycarbonylation, Further reactions

Cascade reaction, 2-(1-phenylpropylidene)-1H-indene-1,3(2H)-dione, (E)-1-bromo-2-(2-nitrovinyl)benzene, tetrahydrofluoren-9-ones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cascade reaction

Cyclopropanation, 3-bromo-1-methylindolin-2-one, 2-benzylidene-1H-indene-1,3(2H)-dione, Bispiro[indanedione-oxindole-cyclopropane], 3-[(3,5-dimethoxyphenyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Cyclopropanation

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