Enantioconvergent Cu-catalysed N-alkylation of aliphatic amines.

DOI Number:

10.1038/s41586-023-05950-8
Link to literature

Reaction Category:

Alkylation | Alkylation | alpha-Amination | Amination

MOP ID:

MOP_0000369

Educt:

aliphatic amines, 2-chloro-N,2-diphenylacetamide

Product:

(S)-2-morpholino-N,2-diphenylacetamide

Catalyst:

copper(I) iodide, N-[(S)-[(1S,2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]oct-2-yl](6-methoxy-4-quinolinyl)methyl]-8-quinolinesulfonamide

Cas No:

1402155-70-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0