Aza-Henry (Nitro-Mannich), amidosulfones, α-aryl nitromethanes, tert-butyl ((1S,2R)-2-nitro-1,2-disubstituted-ethyl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Aza-Henry (Nitro-Mannich), tert-butyl (furan-2-yl(tosyl)methyl)carbamate, nitromethane, orthogonally protected (2S)‐2,3‐diaminopropanoates, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Strecker Reaction, cyclic trifluoromethyl-ketoimines, trimethylsilyl cyanide, substituted 1-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker Aza-Henry (Nitro-Mannich), ketimines, nitromethane, substituted 2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Cyclization, N-(heteroarenesulfonyl)imines, isocyanoacetates, imidazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich Cyclization, α‐imino esters, Isocyanoacetate, substituted 5-((4R,5R)-4-carboxylato-1-(2-hydroxyphenyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations Mannich reaction, azlactones, isatin-derived ketimines, substituted 4-((S)-3-amino-2-oxoindolin-3-yl)oxazol-5(4H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich Mannich reaction, oxazolones, N-protected imines, N-((S)-((R)-4-methyl-5-oxo-2-phenyl-4,5-dihydrooxazol-4-yl)(phenyl)methyl)methanesulfonamide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Mannich reaction, oxazolones, N-tosyl aldimines, substituted 4-methyl-N-((5-oxo-4,5-dihydrooxazol-4-yl)methyl)benzenesulfonamide, (8α,9R)-6′-Methoxy-9-[(trimethylsilyl)oxy]cinchonan, Quinine DerivativeMannich, Mannich Sulfa-Michael Addition, β,β-disubstituted nitroalkenes, para-methylthiophenol, ethyl (S)-3-nitro-2-phenyl-2-(p-tolylthio)propanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition« Older EntriesNext Entries »
Aza-Henry (Nitro-Mannich), amidosulfones, α-aryl nitromethanes, tert-butyl ((1S,2R)-2-nitro-1,2-disubstituted-ethyl)carbamate, (8α,9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-[[[[(1S)-2-hydroxy-1-phenylethyl]amino]carbonyl]amino]-6′-methoxy-cinchonanium bromide, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Aza-Henry (Nitro-Mannich), tert-butyl (furan-2-yl(tosyl)methyl)carbamate, nitromethane, orthogonally protected (2S)‐2,3‐diaminopropanoates, 9-hydroxy-6′-methoxy-1-(phenylmethyl)-cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Strecker Reaction, cyclic trifluoromethyl-ketoimines, trimethylsilyl cyanide, substituted 1-(4-methoxybenzyl)-2-oxo-1,2,3,4-tetrahydroquinazoline-4-carbonitrile, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeStrecker
Aza-Henry (Nitro-Mannich), ketimines, nitromethane, substituted 2-((4-methylphenyl)sulfonamido)-3-nitropropanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Cyclization, N-(heteroarenesulfonyl)imines, isocyanoacetates, imidazolines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations, Mannich, Mannich
Cyclization, α‐imino esters, Isocyanoacetate, substituted 5-((4R,5R)-4-carboxylato-1-(2-hydroxyphenyl)-4,5-dihydro-1H-imidazol-5-yl)oxazole-4-carboxylate, 2-(diphenylphosphino)-N-[(8α,9S)-6′-methoxycinchonan-9-yl]-benzamide, Quinine Derivative[3+2] Annulation, Cyclization, Further Cyclizations
Mannich reaction, azlactones, isatin-derived ketimines, substituted 4-((S)-3-amino-2-oxoindolin-3-yl)oxazol-5(4H)-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
Mannich reaction, oxazolones, N-protected imines, N-((S)-((R)-4-methyl-5-oxo-2-phenyl-4,5-dihydrooxazol-4-yl)(phenyl)methyl)methanesulfonamide, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Mannich reaction, oxazolones, N-tosyl aldimines, substituted 4-methyl-N-((5-oxo-4,5-dihydrooxazol-4-yl)methyl)benzenesulfonamide, (8α,9R)-6′-Methoxy-9-[(trimethylsilyl)oxy]cinchonan, Quinine DerivativeMannich, Mannich
Sulfa-Michael Addition, β,β-disubstituted nitroalkenes, para-methylthiophenol, ethyl (S)-3-nitro-2-phenyl-2-(p-tolylthio)propanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Sulfa-Michael, Sulfa-Michael Addition
