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Aza-Henry (Nitro-Mannich), tert-butyl (Z)-(4-chlorobenzylidene)carbamate, methyl 3-methyl-4-nitrobutanoate, methyl (4S,5R)-5-((tert-butoxycarbonyl)amino)-5-(4-chlorophenyl)-3-methyl-4-nitropentanoate, (1S,2R,4S,5R)-1-benzyl-2-((R)-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Quinidine Derivative

Aza-Henry, Henry, Mannich, Nitro-Mannich

Mannich reaction, malonates, imines, beta-amino acids, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Mannich, Mannich

Sulfa-Michael Addition, (2E, 4E)-6-oxo-2, 4-dienoates, aliphatic thiols, (E)-4-(substituted-thio)-6-oxohex-2-enoate, Quinine Base

Michael Addition, Sulfa-Michael, Sulfa-Michael Addition

Sulfa-Michael Addition, 4-oxo-butenoates, aliphatic thiols, 2-(substituted-thio)-4-oxo-butanoates, Quinine Base

Michael Addition, Sulfa-Michael, Sulfa-Michael Addition

Domino Mannich reaction, 3-isothiocyanato oxindoles, imines, spirocyclic oxindoles, Quinine Base

Cascade reaction, Spirocyclization

Michael Addition, (E)-3-cyclohexyl-1-phenylprop-2-en-1-one, malonitrile, (R)-2-(1-cyclohexyl-3-oxo-3-phenylpropyl)malononitrile, Quinine Base

Michael, Michael Addition

Hydrogenation of alpha-ketoester, ethyl 2-oxopropanoate, hydrogen, ethyl (R)-2-hydroxypropanoate, platinum/aluminiumoxide, Quinine Base

Further reactions, Hydrogenation, Hydrogenation of alpha-ketoesters, Reduction

Desymmetrization by Michael Reaction, cyclohexadienones bearing a bisphenylsulfonyl methylene group, polycyclic cyclohexenones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-ylurea, Cinchonine Derivative

Desymmetrization

Cascade reaction/Cyclization, beta,gamma-unsaturated amides, beta,gamma-unsaturated alpha-ketoesters, 5,6-dihydropyran-2-ones, 1-(3,5-bis(trifluoromethyl)phenyl)-3-((R)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thiourea, Cinchonine Derivative

Cascade reaction, Cyclization, Lactonization

Hydrogenation of ketones, 1-(4-substituted-phenyl)ketones, propan-2-ol, 1-(4-substituted-phenyl)alcohols, propan-2-one, (9S)-Cinchonan-9-amine, Cinchonine Derivative

Further reactions, Hydrogenation, Hydrogenation of ketones

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