Cyclopropanation, 2-bromo-N,N-diethylacetamide, 1-phenylprop-2-en-1-one, (1S,2S)-2-benzoyl-N,N-diethylcyclopropane-1-carboxamide, (8α,9R)-6′,9-Dimethoxycinchonan, Quinine DerivativeCyclopropanation Fluorination, ((2-benzyl-1H-inden-3-yl)oxy)trimethylsilane, Selectfluor, (R)-2-benzyl-2-fluoro-2,3-dihydro-1H-inden-1-one, Polystyrene-bound Quinine BaseFluorination, Fluorination Cascade reaction – Michael, 4-(2-hydroxy-5-isopropyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanal, 1-(triphenyl-lambda5-phosphaneylidene)propan-2-one, (3aR,7S,8S,8aS)-8-acetyl-5-hydroxy-7-isopropyl-1,2,3,7,8,8a-hexahydro-4H-3a,7-methanoazulene-4,9-dione, Quinine BaseCascade reaction, Cyclization Betti reaction, 4-methylpyrimidin-2-amine, quinolin-8-ol, 4-(trifluoromethyl)benzaldehyde, (S)-7-(((4-methylpyrimidin-2-yl)amino)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol, Quinine BaseBetti reaction, Further reactions Desymmetrization of anhydrides, cyclic anhydrides, methanol, methyl monoesters, Quinine BaseDesymmetrization alpha-Arylation of cycloketones, cycloketones, aryl halides, alpha-aryl cycloketones, Palladium(0)-bis(dibenzylidenaceton), Quinine BaseArylation, Further reactions Aza-Henry (Nitro-Mannich), ethyl (E)-2-((4-methoxyphenyl)imino)acetate, tert-butyl 2-nitropropanoate, 1-(tert-butyl) 4-ethyl (2S,3R)-3-((4-methoxyphenyl)amino)-2-methyl-2-nitrosuccinate, Quinine BaseAza-Henry, Henry, Mannich, Nitro-Mannich Henry reaction (Nitroaldol), aromatic or aliphatic aldehydes, alpha substituted nitromethane, beta-nitroalcohols, copper (II) acetate, Quinine BaseAldol, Henry, Henry, Nitroaldol Protonation of alpha-oxygenated ester enolates, alpha-ketoesters, phosphites, alpha-phosphonyloxy esters, Quinine BaseProtonation Spirocyclization/Domino Mannich/Cyclization, 3-isothiocyanato oxindoles, imines, spirocyclic oxindoles, Quinine BaseCascade reaction, Spirocyclization« Older EntriesNext Entries »
Cyclopropanation, 2-bromo-N,N-diethylacetamide, 1-phenylprop-2-en-1-one, (1S,2S)-2-benzoyl-N,N-diethylcyclopropane-1-carboxamide, (8α,9R)-6′,9-Dimethoxycinchonan, Quinine DerivativeCyclopropanation
Fluorination, ((2-benzyl-1H-inden-3-yl)oxy)trimethylsilane, Selectfluor, (R)-2-benzyl-2-fluoro-2,3-dihydro-1H-inden-1-one, Polystyrene-bound Quinine BaseFluorination, Fluorination
Cascade reaction – Michael, 4-(2-hydroxy-5-isopropyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanal, 1-(triphenyl-lambda5-phosphaneylidene)propan-2-one, (3aR,7S,8S,8aS)-8-acetyl-5-hydroxy-7-isopropyl-1,2,3,7,8,8a-hexahydro-4H-3a,7-methanoazulene-4,9-dione, Quinine BaseCascade reaction, Cyclization
Betti reaction, 4-methylpyrimidin-2-amine, quinolin-8-ol, 4-(trifluoromethyl)benzaldehyde, (S)-7-(((4-methylpyrimidin-2-yl)amino)(4-(trifluoromethyl)phenyl)methyl)quinolin-8-ol, Quinine BaseBetti reaction, Further reactions
Desymmetrization of anhydrides, cyclic anhydrides, methanol, methyl monoesters, Quinine BaseDesymmetrization
alpha-Arylation of cycloketones, cycloketones, aryl halides, alpha-aryl cycloketones, Palladium(0)-bis(dibenzylidenaceton), Quinine BaseArylation, Further reactions
Aza-Henry (Nitro-Mannich), ethyl (E)-2-((4-methoxyphenyl)imino)acetate, tert-butyl 2-nitropropanoate, 1-(tert-butyl) 4-ethyl (2S,3R)-3-((4-methoxyphenyl)amino)-2-methyl-2-nitrosuccinate, Quinine BaseAza-Henry, Henry, Mannich, Nitro-Mannich
Henry reaction (Nitroaldol), aromatic or aliphatic aldehydes, alpha substituted nitromethane, beta-nitroalcohols, copper (II) acetate, Quinine BaseAldol, Henry, Henry, Nitroaldol
Protonation of alpha-oxygenated ester enolates, alpha-ketoesters, phosphites, alpha-phosphonyloxy esters, Quinine BaseProtonation
Spirocyclization/Domino Mannich/Cyclization, 3-isothiocyanato oxindoles, imines, spirocyclic oxindoles, Quinine BaseCascade reaction, Spirocyclization
