Direct Access to β-Trifluoromethyl-β-hydroxy Thioesters by Biomimetic Organocatalytic Enantioselective Aldol Reaction.
DOI Number:
10.1021/acs.orglett.9b01469
Reaction Category:
RXNO ID:
RXNO_0000016
Educt:
3-((4-fluorophenyl)thio)-3-oxopropanoic acid, 2,2,2-trifluoro-1-phenylethan-1-one
Product:
S-(4-fluorophenyl) (S)-4,4,4-trifluoro-3-hydroxy-3-phenylbutanethioate
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea
Cas No:
890044-38-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2