Catalytic Enantioselective Iodoetherification of Oximes.

DOI Number:

10.1002/ange.201304173
Link to literature

Reaction Category:

Cyclization | Iodination | Iodoetherification | Isoxazoline cyclization

MOP ID:

MOP_0000554

Educt:

(E)-3-(4-chlorophenyl)-1-phenylbut-3-en-1-one oxime, 1-iodopyrrolidine-2,5-dione

Product:

(S)-5-(4-chlorophenyl)-5-(iodomethyl)-3-phenyl-4,5-dihydroisoxazole

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-10,11-dihydrocinchonan-9-yl]thiourea

Cas No:

1362859-89-9

Associated Product from Buchler GmbH:

Dihydrocinchonidine Base

Cas No:

485-64-3