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Bromolactonization, olefinic acids, N-bromosuccinimide, (6S)-substituted (R)-5-bromo-tetrahydro-2H-pyran-2-one, (9S)-6′-methoxy-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Quinidine Derivative

Cyclization, Lactonization

Trifluoromethylthiolation, azlactones, 2-((trifluoromethyl)thio)isoindoline-1,3-dione, (R)-4-isopropyl-2-(4-methoxyphenyl)-4-((trifluoromethyl)thio)oxazol-5(4H)-one, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-6′-methoxy-cinchonanium bromide, Quinidine Derivative

Trifluoro-methylthiolation

Sulfenylation, deconjugated butyrolactams, 1-((4-fluorophenyl)thio)pyrrolidine-2,5-dione, ethyl (S)-1,4-dibenzyl-4-((4-fluorophenyl)thio)-2-methyl-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate, (9S)-(9′′S)-9,9′′-[1,4-phthalazinediylbis(oxy)]bis[6′-methoxy-cinchonan, Quinidine Derivative

Sulfenylation

Cyclization, gamma-aryl-substituted enals, (E)-substituted nitroethene, cyclohexenol derivatives, (2S)-2-[[2-[[(9R)-6′-methoxycinchonan-9-yl]amino]-3,4-dioxo-1-cyclobuten-1-yl]amino]-3,3-dimethyl-N-(phenylmethyl)-butanamide, Quinidine Derivative

Cyclization, Cyclization, Further Cyclizations

Epoxidation, (E)-substituted methyl 2-cyanoacrylate, tert-butylhydroperoxid, (3R)-substituted methyl (2R)-2-cyanooxirane-2-carboxylate, N-[(1R,2R)-2-amino-1,2-di-1-naphthalenylethyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivative

Epoxidation

Aza-Michael Addition, C/S-substituted N-(2-formylphenyl)sulfonamide, (E)-substituted nitroethene, 3-nitro-1,2-dihydroquinolines, N-[(1R,2S)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-N′-[(9R)-6′-methoxycinchonan-9-yl]-thiourea, Quinidine Derivative

Aza-Henry, Aza-Michael, Henry, Michael Addition

[10+2] Cycloaddition, 2‐alkylidene‐1‐indanones, activated alkenes, ethyl (1S,2S,3S,3aR,8aS)-1′-methyl-6-nitro-2′,8-dioxo-1-phenyl-3,3a,8,8a-tetrahydro-1H-spiro[cyclopenta[a]indene-2,3′-indoline]-3-carboxylate, 9-hydroxy-6′-methoxy-1-[[2,4,6-tris(1-methylethyl)phenyl]methyl]-cinchonanium bromide, Quinidine Derivative

Cyclization, Cycloaddition

Aldol reaction, substituted indoline-2,3-dione, methylketones, 3‐alkyl‐3‐hydroxyindolin‐2‐ones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Aldol, Aldol

Mannich reaction, substituted ((phenylsulfonyl)methyl)carbamate, dibenzyl malonate, substituted dibenzyl 2-((methoxycarbonyl)amino)malonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Mannich, Mannich

Michael Addition, S-methyl 2-cyanopropanethioate, 2-chloroacrylonitrile, S-methyl (2R,4R)-4-chloro-2,4-dicyano-2-methylbutanethioate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative

Michael, Michael Addition

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