Squaramide-catalysed asymmetric Michael addition/cyclization cascade reaction of 4-arylmethylidene-2,3-dioxopyrrolidines with 2- isothiocyanato-1-indanones.

DOI Number:

10.1039/d1ob01223a

Reaction Category:

Educt:

substituted 2-isothiocyanato-2,3-dihydro-1H-inden-1-ones, substituted (E)-4-benzylidene-1-phenylpyrrolidine-2,3-diones

Product:

substituted (2R,3'R,4'S)-1'',3'-diphenyl-5'-thioxodispiro[indene-2,2'-pyrrolidine-4',3''-pyrrolidine]-1,4'',5''(3H)-triones

Catalyst:

(9R)-10,11-Dihydro-6′-methoxycinchonan-9-yl]amino]-4-[(4-nitrophenyl)amino]-4-[(4-nitrophenyl)amino]-3-Cyclobutene-1,2-dione

Cas No:

2691802-13-6

Cas No:

1435-55-8