Angew. Chem. Int. Ed. Archives

Bromination/cyclization, substituted 1-((2-(9H-carbazol-9-yl)phenyl)ethynyl)naphthalen-2-ols, N-bromosuccinimide, substituted 1-(5-bromobenzo[6,7]azepino[3,2,1-jk]carbazol-4-yl)naphthalen-2-ols, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

by Anna-Lena Hartmann | May 3, 2023

Amination, 3-phenylbutan-2-one, di-tert-butyl (E)-diazene-1,2-dicarboxylate, di-tert-butyl (S)-1-(3-oxo-2-phenylbutan-2-yl)hydrazine-1,2-dicarboxylate, trifluoroacetic acid, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

by Anna-Lena Hartmann | Apr 28, 2023

6-pi-electrocylcization, substituted diisopropyl 2-(2-aminophenyl)malonate, aldehydes, substituted diisopropyl indoline-3,3-dicarboxylate, (8α,9R)-9-hydroxy-1-(phenylmethyl)-Cinchonanium chloride, Cinchonidine Derivative

by Anna-Lena Hartmann | Apr 26, 2023

Epoxidation, (E)-6-phenylhex-3-en-2-one, hydrogen peroxide, 1-((2S,3R)-3-phenethyloxiran-2-yl)ethan-1-one, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

by Anna-Lena Hartmann | Apr 19, 2023

Aldol reaction, 4-substituted-2,6-heptanediones, 5-substituted-3-methyl-2-cyclohexene-1-ones, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

by Anna-Lena Hartmann | Apr 19, 2023

Aldol cyclodehydration of 4-substituted-2,6-heptanediones leads to enantiomerically enriched 5-substituted-3-methyl-2-cyclohexene-1-ones, which serve as perfume ingredients and valuable synthetic building blocks. Primary amines derived from cinchona alkaloids in...

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