Buchler Glossary

Tamura Cyclization

In the presence of a Cinchona squaramide-based catalyst, enolizable anhydrides react with alkylidene oxindoles to generate spirooxindole products with excellent enantio- and diastereocontrol.

Tamura cyclization examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.

Example from Literature

Catalytic Asymmetric Tamura Cycloadditions. (Manoni, F., Connon, S. J.; Angew. Chem. Int. Ed. 2014, 53, 2628-2632.)

Tamura cyclization

Further Articles:


1,2-Addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd...