Buchler Glossary

Reformatsky reaction

Reformatsky reaction is an organic reaction which condenses aldehydes or ketones with α-halo esters using metallic zinc to form β-hydroxy-esters.

Reformatsky reaction examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search Data Base.

Example from Literature

Highly Enantioselective Reformatsky Reaction of Ketones: Chelation-Assisted Enantioface Discrimination. (Ojida et al.; Org. Lett. 2002, 4, 3051-3054.)

Reformatsky reaction

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