Highly Enantioselective Reformatsky Reaction of Ketones: Chelation-Assisted Enantioface Discrimination

DOI Number:

10.1021/ol0263189

Reaction Category:

RXNO ID:

RXNO_0000036

Educt:

phenyl(1-trityl-1H-imidazol-4-yl)methanone, (2-(tert-butoxy)-2-oxoethyl)zinc(II) bromide

Product:

tert-butyl (S)-3-hydroxy-3-phenyl-3-(1-trityl-1H-imidazol-4-yl)propanoate

Catalyst:

Cinchonine Base

Cas No:

118-10-5

Cas No:

118-10-5