Buchler Glossary


Cyanation is the attachment or substitution of a cyanide group on various substrates. Such transformations are high-value because they generate C-C bond. Furthermore nitriles are versatile functional groups.

Please find several examples of Cyanation promoted by Cinchona Alkaloids in our Buchler Chiral Catalyst Search.

Example from literature

Asymmetric Cyanation of Activated Olefins with Ethyl Cyanoformate Catalyzed by a Modular Titanium Catalyst. (Wang et al.; Org. Lett. 2010, 12, 6, 1280–1283.)


Further Articles:


1,2-Addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd...