Buchler Glossary

Cyanation

Cyanation is the attachment or substitution of a cyanide group on various substrates. Such transformations are high-value because they generate C-C bond. Furthermore nitriles are versatile functional groups.

Please find several examples of Cyanation promoted by Cinchona Alkaloids in our Buchler Chiral Catalyst Search.

Example from literature

Asymmetric Cyanation of Activated Olefins with Ethyl Cyanoformate Catalyzed by a Modular Titanium Catalyst. (Wang et al.; Org. Lett. 2010, 12, 6, 1280–1283.)

Cyanation

Further Articles:

Alkynylation

Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...

Allylsilylations

Allylsilylations are performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...

Aminohydroxylation

The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...