Buchler Glossary


Cross-coupling reactions occur when two reagents, both with activating groups, react together with a metal catalyst to form a new covalent bond, driven by loss of the activating groups. Pd is the principle catalyst metal. The 2010 Nobel Prize in Chemistry was awarded to Richard Heck, Ei-ichi Negishi, and Akira Suzuki for their contributions to the development of Pd-catalyzed C-C bond forming reactions.

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1,2-Addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd...