Buchler Glossary

Cross-coupling

Cross-coupling reactions occur when two reagents, both with activating groups, react together with a metal catalyst to form a new covalent bond, driven by loss of the activating groups. Pd is the principle catalyst metal. The 2010 Nobel Prize in Chemistry was awarded to Richard Heck, Ei-ichi Negishi, and Akira Suzuki for their contributions to the development of Pd-catalyzed C-C bond forming reactions.

Further Articles:

Alkynylation

Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...

Allylsilylations

Allylsilylations are performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...

Aminohydroxylation

The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...