Buchler Glossary

1,2-Addition

1,2-Addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd carbon atoms of a carbon chain. In other words, the functional groups in the product of this reaction are attached to the adjacent carbon atoms.

1,2-Addition examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.

Further Articles:

Alkynylation

Alkynylation is an addition reaction in organic synthesis where a terminal alkyne adds to a carbonyl group to form an...

Allylsilylations

Allylsilylations are performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...

Aminohydroxylation

The Sharpless Aminohydroxylation allows the syn-selective preparation of 1,2-amino alcohols by reaction of alkenes...