Buchler Glossary

1,2-Addition

1,2-Addition is a type of organic chemical reaction that involves the addition of functional groups to the 1st and 2nd carbon atoms of a carbon chain. In other words, the functional groups in the product of this reaction are attached to the adjacent carbon atoms.

1,2-Addition examples catalyzed by cinchona alkaloid derivatives can be found in our free of charge Chiral Catalyst Search.

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Asymmetric Alkylation

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Asymmetric Amination

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