[3+2] Cycloaddtion, substituted 3-isothiocyanato oxindoles, substituted 2-nitrobenzo heteroarenes, polycyclic spirooxindoles, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine Derivative[3+2]-Cycloaddition, Cycloaddition Epoxidation, (E)-1-phenylhept-2-en-1-one, sodium hypochlorite, ((2S,3R)-3-butyloxiran-2-yl)(phenyl)methanone, O-Benzyl-1-(9-anthracenylmethyl)-dihydrocinchonidinium Bromide, Dihydrocinchonidine DerivativeEpoxidation Hydrophosphonylation, substituted tert-butyl (E)-(2-oxoindolin-3-ylidene)carbamate, diphenyl phosphite, substituted tert-butyl (R)-(3-(diphenoxyphosphoryl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeHydrophosphonylation Michael Addition, ethyl (E)-3-(3-(2-aminoethyl)-1-tosyl-1H-indol-4-yl)acrylate, ethyl 2-((4R,5R)-4-nitro-1-tosyl-1,3,4,5-tetrahydroacenaphthylen-5-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, tert-butyl (Z)-3-(3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-ylidene)-2-oxoindoline-1-carboxylate, nitromethane, tert-butyl (S)-3-((S)-3-ethoxy-1,1,1-trifluoro-2-(nitromethyl)-3-oxopropan-2-yl)-2-oxoindoline-1-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael, Michael Addition Tamura cyclization, isochromane-1,3-dione, tert-butyl (E)-3-(2-ethoxy-2-oxoethylidene)-2-oxoindoline-1-carboxylate, methanol, 1-(tert-butyl) 3′-ethyl 4′-methyl (3R,3’R,4’R)-1′,2-dioxo-3′,4′-dihydro-1’H-spiro[indoline-3,2′-naphthalene]-1,3′,4′-tricarboxylate, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cycloaddition, Spirocyclization Michael Addition, (E)-1,3-difluoro-5-(2-nitrovinyl)benzene, (fluoro(nitro)methyl)benzene, 1,3-difluoro-5-((1R,2S)-1-fluoro-1,3-dinitro-1-phenylpropan-2-yl)benzene, (2S,3R)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-butanamide, Cinchonidine DerivativeMichael, Michael Addition alpha-hydroxylation, methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, methyl (S)-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, Cumene hydroperoxide, (9S)-2′-bromo-10,11-dihydro-cinchonan-6′,9-diol, Cupreidine DerivativeHydroxylation Mannich reaction, unfunctionalized ketones, 4-methylbenzenesulfonamide, substituted benzaldehydes, substituted (S)-4-methyl-N-(3-oxo-1-phenylpropyl)benzenesulfonamide, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]-thiourea, 6´-Aminocinchonine DerivativeMannich, Mannich Amination, 2,2,3,3,4,4,4-heptafluorobutyl sulfamate, 4-phenylbutan-1-ol, 2,2,3,3,4,4,4-heptafluorobutyl (R)-(4-hydroxy-1-phenylbutyl)sulfamate, ruthenium(II), (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-cinchonanium bromide, Dihydroquinidine DerivativeAmination« Older EntriesNext Entries »
[3+2] Cycloaddtion, substituted 3-isothiocyanato oxindoles, substituted 2-nitrobenzo heteroarenes, polycyclic spirooxindoles, (αS)-α-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-benzenepropanamide, Cinchonidine Derivative[3+2]-Cycloaddition, Cycloaddition
Epoxidation, (E)-1-phenylhept-2-en-1-one, sodium hypochlorite, ((2S,3R)-3-butyloxiran-2-yl)(phenyl)methanone, O-Benzyl-1-(9-anthracenylmethyl)-dihydrocinchonidinium Bromide, Dihydrocinchonidine DerivativeEpoxidation
Hydrophosphonylation, substituted tert-butyl (E)-(2-oxoindolin-3-ylidene)carbamate, diphenyl phosphite, substituted tert-butyl (R)-(3-(diphenoxyphosphoryl)-2-oxoindolin-3-yl)carbamate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeHydrophosphonylation
Michael Addition, ethyl (E)-3-(3-(2-aminoethyl)-1-tosyl-1H-indol-4-yl)acrylate, ethyl 2-((4R,5R)-4-nitro-1-tosyl-1,3,4,5-tetrahydroacenaphthylen-5-yl)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, tert-butyl (Z)-3-(3-ethoxy-1,1,1-trifluoro-3-oxopropan-2-ylidene)-2-oxoindoline-1-carboxylate, nitromethane, tert-butyl (S)-3-((S)-3-ethoxy-1,1,1-trifluoro-2-(nitromethyl)-3-oxopropan-2-yl)-2-oxoindoline-1-carboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael, Michael Addition
Tamura cyclization, isochromane-1,3-dione, tert-butyl (E)-3-(2-ethoxy-2-oxoethylidene)-2-oxoindoline-1-carboxylate, methanol, 1-(tert-butyl) 3′-ethyl 4′-methyl (3R,3’R,4’R)-1′,2-dioxo-3′,4′-dihydro-1’H-spiro[indoline-3,2′-naphthalene]-1,3′,4′-tricarboxylate, 3-[(1,1-dimethylethyl)amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cycloaddition, Spirocyclization
Michael Addition, (E)-1,3-difluoro-5-(2-nitrovinyl)benzene, (fluoro(nitro)methyl)benzene, 1,3-difluoro-5-((1R,2S)-1-fluoro-1,3-dinitro-1-phenylpropan-2-yl)benzene, (2S,3R)-2-[[[[3,5-bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(8α,9S)-cinchonan-9-yl-3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-butanamide, Cinchonidine DerivativeMichael, Michael Addition
alpha-hydroxylation, methyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylate, methyl (S)-2-hydroxy-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, Cumene hydroperoxide, (9S)-2′-bromo-10,11-dihydro-cinchonan-6′,9-diol, Cupreidine DerivativeHydroxylation
Mannich reaction, unfunctionalized ketones, 4-methylbenzenesulfonamide, substituted benzaldehydes, substituted (S)-4-methyl-N-(3-oxo-1-phenylpropyl)benzenesulfonamide, N-[3,5-bis(trifluoromethyl)phenyl]-N′-[(9S)-9-(phenylmethoxy)cinchonan-6′-yl]-thiourea, 6´-Aminocinchonine DerivativeMannich, Mannich
Amination, 2,2,3,3,4,4,4-heptafluorobutyl sulfamate, 4-phenylbutan-1-ol, 2,2,3,3,4,4,4-heptafluorobutyl (R)-(4-hydroxy-1-phenylbutyl)sulfamate, ruthenium(II), (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-cinchonanium bromide, Dihydroquinidine DerivativeAmination