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Desymmetrization, tert-butyl 2-oxo-3-phenylindoline-1-carboxylate, 1-(2-(tert-butyl)phenyl)-1H-pyrrole-2,5-dione, tert-butyl (R)-3-((S)-1-(2-(tert-butyl)phenyl)-2,5-dioxopyrrolidin-3-yl)-2-oxo-3-phenylindoline-1-carboxylate, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine Derivative

Atropisomer synthesis, Desymmetrization

Spirocyclization, 2-alkylidene benzo[b]thiophenone derivatives, substituted enones, substituted spirocyclic benzothiophenones, 4-nitrobenzoic acid, (8α,9S)-Cinchonan-9-amine, Cinchonidine Derivative

Spirocyclization

Mannich reaction, α-ketoester derived ketimines, Malononitrile, α-amino-β,β-dicyanoesters, diethylzinc, N-(8α,9S)-Cinchonan-9-yl-8-quinolinesulfonamide, Cinchonidine Derivative

Mannich, Mannich

Biginelli reaction, ethyl 3-oxobutanoate, urea, benzaldehyde, ethyl (R)-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carboxylate, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Biginelli reaction

1,3-dipolar Cycloaddition, 2,4,6-Trimethylbenzonitrile oxide, 2-methoxy-6-vinylphenol, (S)-2-(3-mesityl-4,5-dihydroisoxazol-5-yl)-6-methoxyphenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine Derivative

1,3-Dipolar Cycloaddition, Cycloaddition, Isoxazoline cyclization

1,3-dipolar Cycloaddition, (Z)-N-hydroxycyclohexanecarbimidoyl chloride, 2-methoxy-6-vinylphenol, (S)-2-(3-cyclohexyl-4,5-dihydroisoxazol-5-yl)-6-methoxyphenol, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]urea, Quinine Derivative

1,3-Dipolar Cycloaddition, Cyclization, Cycloaddition, Isoxazoline cyclization

Michael Addition, (E)-(2-nitrovinyl)benzene, 3-((4-methoxyphenyl)thio)-3-oxopropanoic acid, S-(4-methoxyphenyl) (S)-4-nitro-3-phenylbutanethioate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael, Michael Addition

[2+2]-Cycloaddition, acid chlorides, ethyl (E)-2-(tosylimino)acetate, β-lactams, Benzolyquinine, Quinine Derivative

[2+2]-Cycloaddition, Cycloaddition

Vinylogous Michael Addition, 3-ethylcyclohex-2-en-1-one, N-(2-tert-Butylphenyl)maleimide, (R)-1-(2-(tert-butyl)phenyl)-3-((R)-1-(3-oxocyclohex-1-en-1-yl)ethyl)pyrrolidine-2,5-dione, N-Boc-L-phenylglycine, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Atropisomer synthesis, Michael Addition, Vinylogous Michael Addition

Diels-Alder Desymmetrization, N-(2-tert-butylphenyl)maleimide, (E)-4-phenylbut-3-en-2-one, (3aR,7S,7aS)-2-(2-(tert-butyl)phenyl)-7-phenyltetrahydro-1H-isoindole-1,3,5(2H,4H)-trione, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

Atropisomer synthesis, Cycloaddition, Desymmetrization, Diels-Alder reaction

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