aza-Henry reaction, substituted tert-butyl (tosylmethyl)carbamate, nitroalkanes, subsituted tert-butyl (2-nitroethyl)carbamate, 9-hydroxy-6′-methoxy-1-(phenylmethyl)- cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Desymmetrization, (3aR,7aS)-hexahydroisobenzofuran-1,3-dione, alcohols, (1R,2S)-2-ester-cyclohexane-1-carboxylic acid, 1,2,2,6,6-pentamethylpiperidine, Quinine BaseDesymmetrization Alkylation, substituted N-phenethylformimidoyl cyanide, acrylaldehyde, substituted (S)-N-(5-hydroxy-1-phenylpentan-2-yl)formimidoyl cyanide, (1S,2R,4S,5R)-1-((2′-(tert-butoxy)-3,3”,5,5”-tetra-tert-butyl-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)-2-((S)-((6-chloro-2,5-diphenylpyrimidin-4-yl)oxy)(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Cinchonine DerivativeAlkylation, Alkylation Michael Addition, pentane-2,4-dione, (E)-(2-nitrovinyl)benzene, (R)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael, Michael Addition Hetero Diels-Alder, indoline-2,3-dione, (E)-5-methylhex-3-en-2-one, (3S,6’S)-6′-isopropyl-5′,6′-dihydrospiro[indoline-3,2′-pyran]-2,4′(3’H)-dione, N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-Threonine, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction Cascade Reaction, substituted 2-methylenemalononitrile, substituted 4-hydroxy-2H-chromen-2-one, substituted 2-amino-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Hydrogenation, 1-(o-tolyl)ethan-1-one, (S)-1-(o-tolyl)ethan-1-ol, Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]diiridium, N-[[2-[bis(2-methoxyphenyl)phosphino]phenyl]methyl]-(8α,9S)-cinchonan-9-amine, Cinchonidine DerivativeHydrogenation, Hydrogenation of ketones Chlorocyclization, substituted N-(2-vinylphenyl)amide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-4H-benzo[d][1,3]oxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations Chlorocyclization, substituted tert-butyl (2-vinylphenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, trimethyl(trifluoromethyl)silane, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeTrifluoromethylation« Older EntriesNext Entries »
aza-Henry reaction, substituted tert-butyl (tosylmethyl)carbamate, nitroalkanes, subsituted tert-butyl (2-nitroethyl)carbamate, 9-hydroxy-6′-methoxy-1-(phenylmethyl)- cinchonanium chloride, Quinine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Desymmetrization, (3aR,7aS)-hexahydroisobenzofuran-1,3-dione, alcohols, (1R,2S)-2-ester-cyclohexane-1-carboxylic acid, 1,2,2,6,6-pentamethylpiperidine, Quinine BaseDesymmetrization
Alkylation, substituted N-phenethylformimidoyl cyanide, acrylaldehyde, substituted (S)-N-(5-hydroxy-1-phenylpentan-2-yl)formimidoyl cyanide, (1S,2R,4S,5R)-1-((2′-(tert-butoxy)-3,3”,5,5”-tetra-tert-butyl-[1,1′:3′,1”-terphenyl]-5′-yl)methyl)-2-((S)-((6-chloro-2,5-diphenylpyrimidin-4-yl)oxy)(quinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide, Cinchonine DerivativeAlkylation, Alkylation
Michael Addition, pentane-2,4-dione, (E)-(2-nitrovinyl)benzene, (R)-3-(2-nitro-1-phenylethyl)pentane-2,4-dione, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeMichael, Michael Addition
Hetero Diels-Alder, indoline-2,3-dione, (E)-5-methylhex-3-en-2-one, (3S,6’S)-6′-isopropyl-5′,6′-dihydrospiro[indoline-3,2′-pyran]-2,4′(3’H)-dione, N,N′-Bis[3,5-bis(trifluoromethyl)phenyl]thiourea, N-[(1,1-dimethylethoxy)carbonyl]-O-(1,1-dimethylethyl)-L-Threonine, (8α,9S)-Cinchonan-9-amine, Cinchonidine DerivativeCycloaddition, Diels-Alder reaction
Cascade Reaction, substituted 2-methylenemalononitrile, substituted 4-hydroxy-2H-chromen-2-one, substituted 2-amino-5-oxo-4H,5H-pyrano[3,2-c]chromene-3-carbonitrile, 3-[(8α,9S)-cinchonan-9-ylamino]-4-[[[(1R,4aS,10aR)-1,2,3,4,4a,9,10,10a-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenyl]methyl]amino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Hydrogenation, 1-(o-tolyl)ethan-1-one, (S)-1-(o-tolyl)ethan-1-ol, Di-μ-chlorobis[(1,2,5,6-η)-1,5-cyclooctadiene]diiridium, N-[[2-[bis(2-methoxyphenyl)phosphino]phenyl]methyl]-(8α,9S)-cinchonan-9-amine, Cinchonidine DerivativeHydrogenation, Hydrogenation of ketones
Chlorocyclization, substituted N-(2-vinylphenyl)amide, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-4H-benzo[d][1,3]oxazine, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations
Chlorocyclization, substituted tert-butyl (2-vinylphenyl)carbamate, 1,3-dichloro-5,5-dimethylimidazolidine-2,4-dione, substituted (S)-4-(chloromethyl)-1,4-dihydro-2H-benzo[d][1,3]oxazin-2-one, 9-[2-[bis(2-methylphenyl)amino]benzoate]-(8α,9R)-Cinchonan-9-ol, Cinchonidine DerivativeChlorination, Cyclization
Trifluoromethylation, 4-bromo-2-(3-hydroxy-3-methylbutoxy)-9H-fluoren-9-one, trimethyl(trifluoromethyl)silane, (R)-4-bromo-2-(3-hydroxy-3-methylbutoxy)-9-(trifluoromethyl)-9H-fluoren-9-ol, 1-[[4-(1,1-dimethylethyl)-3-methoxyphenyl]methyl]-9-hydroxy-(8α,9R)-cinchonanium bromide, Cinchonidine DerivativeTrifluoromethylation
