[4+2] Annulation, substituted benzo[e][1,2,3]oxathiazine 2,2-dioxide, substituted (E)-pent-2-en-1-one, 1,3‐oxazinanes, hexahydropyrimidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine Derivative[4+2] Annulation, Cyclization, Further Cyclizations Desymmetrization, tert-butyl 7-fluoro-2-oxo-3-phenylindoline-1-carboxylate, 1-(2-(tert-butyl)phenyl)-1H-pyrrole-2,5-dione, tert-butyl (R)-3-((S)-1-(2-(tert-butyl)phenyl)-2,5-dioxopyrrolidin-3-yl)-7-fluoro-2-oxo-3-phenylindoline-1-carboxylate, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAtropisomer synthesis, Desymmetrization Spirocyclization, N-substituted (Z)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, Aryl substituted alkenes, substituted (3S,5’S)-5′-(trifluoromethyl)spiro[indoline-3,2′-pyrrolidin]-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeSpirocyclization Cascade reaction, substituted 2-mercaptobenzaldehyde, substituted 1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one, substituted (2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)((3S,4R)-4-hydroxythiochroman-3-yl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Cascade reaction, substituted (E)-3-trifluoromethyl-3-(1H-indol-3-yl)-1-phenylprop-2-en-1-one, substituted 2-mercaptobenzaldehyde, substituted ((2R,3S,4R)-4-hydroxy-2-((S)-indolin-3-yl)-2-(trifluoromethyl)thiochroman-3-yl)(phenyl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Pictet-Spengler Reaction, (E)-tert-butyl (4-((2-(4-methoxy-1H-indol-3-yl)ethyl)amino)but-2-en-1-yl) carbonate, methyl 2,2-bis(ethylthio)-5-oxopentanoate, methyl (S,E)-4-(2-(4-((tert-butoxycarbonyl)oxy)but-2-en-1-yl)-5-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-2,2-bis(ethylthio)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction Michael Addition, 3-(2-phenylallyl)benzo[b]thiophen-2(3H)-one, (E)-(2-nitrovinyl)benzene, (S)-3-((R)-2-nitro-1-phenylethyl)-3-(2-phenylallyl)benzo[b]thiophen-2(3H)-one, N-(8α,9S)-cinchonan-9-yl-phosphoramidic acid diethyl ester, Cinchonidine DerivativeMichael, Michael Addition Michael Addition, substituted 4-nitro-5-styrylisoxazoles, substituted nitroalkanes, substituted 3-methyl-4-nitro-5-(3-nitropropyl)isoxazole, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-(9R)-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition Cascade reaction, substituted 2-mercaptobenzaldehyde, substituted 1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one, substituted (2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)((3S,4R)-4-hydroxythiochroman-3-yl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction Friedel Crafts reaction, substituted phenols, trihaloacetaldehydes, trihalohydroxyalkylated phenol adducts, 3,5-dinitro-N-((S)-quinolin-4-yl((1S,2S,4S,5R)- 5-vinylquinuclidin-2-yl)methyl)benzamide, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction« Older EntriesNext Entries »
[4+2] Annulation, substituted benzo[e][1,2,3]oxathiazine 2,2-dioxide, substituted (E)-pent-2-en-1-one, 1,3‐oxazinanes, hexahydropyrimidines, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine Derivative[4+2] Annulation, Cyclization, Further Cyclizations
Desymmetrization, tert-butyl 7-fluoro-2-oxo-3-phenylindoline-1-carboxylate, 1-(2-(tert-butyl)phenyl)-1H-pyrrole-2,5-dione, tert-butyl (R)-3-((S)-1-(2-(tert-butyl)phenyl)-2,5-dioxopyrrolidin-3-yl)-7-fluoro-2-oxo-3-phenylindoline-1-carboxylate, 3-[[[3,5-bis(trifluoromethyl)phenyl]methyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeAtropisomer synthesis, Desymmetrization
Spirocyclization, N-substituted (Z)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, Aryl substituted alkenes, substituted (3S,5’S)-5′-(trifluoromethyl)spiro[indoline-3,2′-pyrrolidin]-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeSpirocyclization
Cascade reaction, substituted 2-mercaptobenzaldehyde, substituted 1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one, substituted (2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)((3S,4R)-4-hydroxythiochroman-3-yl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Cascade reaction, substituted (E)-3-trifluoromethyl-3-(1H-indol-3-yl)-1-phenylprop-2-en-1-one, substituted 2-mercaptobenzaldehyde, substituted ((2R,3S,4R)-4-hydroxy-2-((S)-indolin-3-yl)-2-(trifluoromethyl)thiochroman-3-yl)(phenyl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Pictet-Spengler Reaction, (E)-tert-butyl (4-((2-(4-methoxy-1H-indol-3-yl)ethyl)amino)but-2-en-1-yl) carbonate, methyl 2,2-bis(ethylthio)-5-oxopentanoate, methyl (S,E)-4-(2-(4-((tert-butoxycarbonyl)oxy)but-2-en-1-yl)-5-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)-2,2-bis(ethylthio)butanoate, N-[3,5-Bis(trifluoromethyl)phenyl]- N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeCyclization, Further Cyclizations, Pictet-Spengler Reaction
Michael Addition, 3-(2-phenylallyl)benzo[b]thiophen-2(3H)-one, (E)-(2-nitrovinyl)benzene, (S)-3-((R)-2-nitro-1-phenylethyl)-3-(2-phenylallyl)benzo[b]thiophen-2(3H)-one, N-(8α,9S)-cinchonan-9-yl-phosphoramidic acid diethyl ester, Cinchonidine DerivativeMichael, Michael Addition
Michael Addition, substituted 4-nitro-5-styrylisoxazoles, substituted nitroalkanes, substituted 3-methyl-4-nitro-5-(3-nitropropyl)isoxazole, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-(9R)-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition
Cascade reaction, substituted 2-mercaptobenzaldehyde, substituted 1-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)prop-2-en-1-one, substituted (2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-1-yl)((3S,4R)-4-hydroxythiochroman-3-yl)methanone, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeCascade reaction
Friedel Crafts reaction, substituted phenols, trihaloacetaldehydes, trihalohydroxyalkylated phenol adducts, 3,5-dinitro-N-((S)-quinolin-4-yl((1S,2S,4S,5R)- 5-vinylquinuclidin-2-yl)methyl)benzamide, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction
