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[2+2] Cycloaddition, ketenes, imines, azetidin-2-ones, Benzoylquinine, Quinine Derivative

[2+2]-Cycloaddition, Cycloaddition

Phospha Michael Addition, iminochromenes, dibenzyl phosphonate, dibenzyl (S)-(2-amino-3-cyano-4H-chromen-4-yl)phosphonate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Michael Addition, Phospha-Michael Addition

Michael Addition, kojic acid derivatives, β-nitroolefins, 6-((tert-butyldimethylsilyl)oxy)-3-hydroxy-2-(2-nitro-1-phenylethyl)-4H-pyran-4-one, (2R,3R,4S,5R,6R)-2-(acetoxymethyl)-6-(3-((R)-(6-methoxyquinolin-4-yl)((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methyl)thioureido)tetrahydro-2H-pyran-3,4,5-triyl triacetate, Quinidine Derivative

Michael, Michael Addition

Friedel-Crafts, Indoles, substituted (E)-2-nitro-3-phenylallyl acetate, substituted (3S,4R)-3-nitro-4-phenyl-2,3,4,7-tetrahydropyrano[2,3-e]indole, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Quinine Derivative

Friedel-Crafts, Friedel-Crafts alkylation

Mannich reaction, isatin-derived ketimines, pyrazoleamides, substituted (R)-3-amino-3-(2-oxo-2-(1H-pyrazol-1-yl)ethyl)indolin-2-one, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-4-nitro-benzenesulfonamide, Quinine Derivative

Mannich, Mannich

Spirocyclization, isatins, isocyanoacetates, substituted 4’H-spiro[indoline-3,5′-oxazol]-2-one, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-methanesulfonamide, Quinine Derivative

[3+2]-Cycloaddition, Cycloaddition, Spirocyclization

Michael Addition, 3‐aryloxindoles, (vinylsulfonyl)benzene, 3R-substituted tert-butyl (S)-2-oxo-3-(2-(phenylsulfonyl)ethyl)indoline-1-carboxylate, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-methanesulfonamide, Quinine Derivative

Michael, Michael Addition

Michael Addition, nitroalkenes, curcumin derivatives, substituted 4-(2-nitroethyl)hepta-1,6-diene-3,5-dione, N-[(1S,2S)-2-[[[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]thioxomethyl]amino]-1,2-diphenylethyl]-4-nitro-benzenesulfonamide, Quinine Derivative

Michael, Michael Addition

Friedel-Crafts Alkylation, imines, indoles, 3-subtituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine derivative

Friedel-Crafts, Friedel-Crafts alkylation

Decarboxylative protonation, subtituted 2-(ethoxycarbonyl)-4-oxopentanoic acid, 2R-substituted ethyl 4-oxopentanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Decarboxylative Protonation, Protonation

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