Synthesis of Spiro-Δ2-Pyrrolin-4-One Pseudo Enantiomers via an Organocatalyzed Sulfa-Michael/Aldol Domino Sequence.
DOI Number:
10.1002/adsc.201900747
Reaction Category:
Educt:
methyl (5E)-4,5-dihydro-1,2-dimethyl-4-oxo-5-(phenylmethylene)-1H-pyrrole-3-carboxylate, 1,4-dithiane-2,5-diol
Product:
methyl (5S,6R,9S)-9-hydroxy-1,2-dimethyl-4-oxo-6-phenyl-7-thia-1-azaspiro[4.4]non-2-ene-3-carboxylate
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7
Associated Product from Buchler GmbH:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-84-7