Atropisomer Synthesis, substituted 2-(2-(diphenylphosphoryl)naphthalen-1-yl)pyrimidin-4(3H)-one, 1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene, axially ahiral quinazolinones, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-nitrophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis Oxa-Michael Addition, γ-hydroxy-α,β-unsaturated ketones, ketones, 1,3-dioxolanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Michael Addition, Oxa-Michael Addition Michael Addition, (E)-2-(allyloxy)-1-methoxy-3-(2-nitrovinyl)benzene, dimethyl malonate, 7-ring O-heterocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition Thiolation, sulfonyl indoles, triphenylmethanethiol, 3-sec-sulfur-substituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFurther reactions, Thiolation Oxa-Michael, (E)-7-oxo-7-phenylhept-5-enal, methyl (E)-2-oxo-4-phenylbut-3-enoate, pyrano [2,3‐b] pyrans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCycloaddition, Diels-Alder reaction, Michael Addition, Oxa-Michael Addition Aldol reaction, 1-(p-tolyl)ethan-1-one, isatin containing bisphosphonates, indolin containing bisphosphonates, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol Aldol reaction, 5-methoxyindoline-2,3-dione, methyl 3-oxobutanoate, methyl (R)-4-(3-hydroxy-5-methoxy-2-oxoindolin-3-yl)-3-oxobutanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol Spirocyclization, N-benzyl-2-(1H-indol-3-yl)ethan-1-amine, 1-benzylindoline-2,3-dione, (S)-1,2′-dibenzyl-2′,3′,4′,9′-tetrahydrospiro[indoline-3,1′-pyrido[3,4-b]indol]-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeSpirocyclization Atropisomer Synthesis, substituted 2-(amino(phenyl)methylene)malonate, brominated hydrocarbons, atropisomers, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis Cross-Coupling, cyclopropyl halides, terminal alkynes, alkynyl cyclopropanes, copper(II) triflate, N-[(8α,9R)-2′-butyl-6′-methoxycinchonan-9-yl]-1-isoquinolinecarboxamide, Quinidine DerivativeCross Coupling« Older EntriesNext Entries »
Atropisomer Synthesis, substituted 2-(2-(diphenylphosphoryl)naphthalen-1-yl)pyrimidin-4(3H)-one, 1-(bromomethyl)-3,5-bis(trifluoromethyl)benzene, axially ahiral quinazolinones, (8α,9R)-9-hydroxy-6′-methoxy-1-[(2-nitrophenyl)methyl]-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis
Oxa-Michael Addition, γ-hydroxy-α,β-unsaturated ketones, ketones, 1,3-dioxolanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine Derivative[3+2]-Cycloaddition, Cycloaddition, Michael Addition, Oxa-Michael Addition
Michael Addition, (E)-2-(allyloxy)-1-methoxy-3-(2-nitrovinyl)benzene, dimethyl malonate, 7-ring O-heterocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCyclization, Cyclization, Further Cyclizations, Michael, Michael Addition
Thiolation, sulfonyl indoles, triphenylmethanethiol, 3-sec-sulfur-substituted indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeFurther reactions, Thiolation
Oxa-Michael, (E)-7-oxo-7-phenylhept-5-enal, methyl (E)-2-oxo-4-phenylbut-3-enoate, pyrano [2,3‐b] pyrans, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeCycloaddition, Diels-Alder reaction, Michael Addition, Oxa-Michael Addition
Aldol reaction, 1-(p-tolyl)ethan-1-one, isatin containing bisphosphonates, indolin containing bisphosphonates, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol
Aldol reaction, 5-methoxyindoline-2,3-dione, methyl 3-oxobutanoate, methyl (R)-4-(3-hydroxy-5-methoxy-2-oxoindolin-3-yl)-3-oxobutanoate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeAldol, Aldol
Spirocyclization, N-benzyl-2-(1H-indol-3-yl)ethan-1-amine, 1-benzylindoline-2,3-dione, (S)-1,2′-dibenzyl-2′,3′,4′,9′-tetrahydrospiro[indoline-3,1′-pyrido[3,4-b]indol]-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea, Quinidine DerivativeSpirocyclization
Atropisomer Synthesis, substituted 2-(amino(phenyl)methylene)malonate, brominated hydrocarbons, atropisomers, (9S)-2′-[3,5-bis(1,1-dimethylethyl)phenyl]-9-[[3,5-bis(trifluoromethyl)phenyl]methoxy]-1-[(3,4,5-trifluorophenyl)methyl]-6′-methoxy-cinchonanium bromide, Quinidine DerivativeAtropisomer synthesis
Cross-Coupling, cyclopropyl halides, terminal alkynes, alkynyl cyclopropanes, copper(II) triflate, N-[(8α,9R)-2′-butyl-6′-methoxycinchonan-9-yl]-1-isoquinolinecarboxamide, Quinidine DerivativeCross Coupling
