Cyclopropanation, α,β-unsaturated nitroalkenes, dimethyl 2-bromomalonate, nitrocyclopropanes, Cupreine BaseCyclopropanation Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-Cinchonanium chloride, Cinchonidine DerivativeAlkylation, Alkylation Michael Addition, Diethyl P-(2-oxo-2-phenylethyl)phosphonate, 1-Methoxy-2-[(1E)-2-nitroethenyl]benzene, Diethyl P-[(1R,2R)-1-benzoyl-2-(2-methoxyphenyl)-3-nitropropyl]phosphonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9R)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition [3+2]-Cycloaddition, (E)-4-hydroxy-1-(naphthalen-2-yl)but-2-en-1-one, p-Toluenesulfonyl isocyanate, (R)-4-(2-(naphthalen-2-yl)-2-oxoethyl)-3-tosyloxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine Derivative[3+2]-Cycloaddition, Cyclization, Cycloaddition Michael Addition, 2‐oxindole‐3‐carboxylate esters, nitroolefins, substituted (S)-3-(2-nitroethyl)-2-oxoindoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition Spirocyclization, Methyl 1-tert-butyl-2-hydroxypyrrolo[2,3-b]pyridine-3-carboxylate, (2-(Chloromethyl)-4-(dibenzylamino)phenyl)methanol hydrochloride, (2R)-5-[Bis(phenylmethyl)amino]-1′-(1,1-dimethylethyl)-1,3-dihydrospiro[2H-indene-2,3′-[3H]pyrrolo[2,3-b]pyridin]-2′(1′H)-on, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-(9R)-cinchonanium bromide, Cinchonidine DerivativeSpirocyclization Desymmetrization, (2α,6α)-tetrahydro-1-methyl-4-oxo-2,6-diphenyl-2H-Thiopyranium tetrafluoroborate(1-), (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeDesymmetrization Friedel-Crafts reaction, isatins, 1-naphthols, 3-aryl-3-hydroxy-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction Friedel-Crafts reaction, 1-Benzyl-5-bromoisatin, 3-Methoxyphenol, (3R)-5-Bromo-1,3-dihydro-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1-(phenylmethyl)-2H-indol-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction Trifluoromethylthiolation, methyl 7-bromo-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate, Trichloroisocyanuric Acid, Trifluoromethanethiol silver salt, methyl (S)-7-bromo-1-oxo-2-((trifluoromethyl)thio)-1,2,3,4-tetrahydronaphthalene-2-carboxylate, 3-[(8α,9S)-Cinchonan-9-ylamino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylthiolation« Older EntriesNext Entries »
Cyclopropanation, α,β-unsaturated nitroalkenes, dimethyl 2-bromomalonate, nitrocyclopropanes, Cupreine BaseCyclopropanation
Alkylation, 6,7-dichloro-5-methoxy-2-phenyl-2,3-dihydro-1H-inden-1-one, chloromethane, (S)-6,7-dichloro-5-methoxy-2-methyl-2-phenyl-2,3-dihydro-1H-inden-1-one, (8α,9R)-9-hydroxy-1-[[4-(trifluoromethyl)phenyl]methyl]-Cinchonanium chloride, Cinchonidine DerivativeAlkylation, Alkylation
Michael Addition, Diethyl P-(2-oxo-2-phenylethyl)phosphonate, 1-Methoxy-2-[(1E)-2-nitroethenyl]benzene, Diethyl P-[(1R,2R)-1-benzoyl-2-(2-methoxyphenyl)-3-nitropropyl]phosphonate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9R)-cinchonan-9-ylthiourea, Cinchonidine DerivativeMichael, Michael Addition
[3+2]-Cycloaddition, (E)-4-hydroxy-1-(naphthalen-2-yl)but-2-en-1-one, p-Toluenesulfonyl isocyanate, (R)-4-(2-(naphthalen-2-yl)-2-oxoethyl)-3-tosyloxazolidin-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine Derivative[3+2]-Cycloaddition, Cyclization, Cycloaddition
Michael Addition, 2‐oxindole‐3‐carboxylate esters, nitroolefins, substituted (S)-3-(2-nitroethyl)-2-oxoindoline-3-carboxylate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition
Spirocyclization, Methyl 1-tert-butyl-2-hydroxypyrrolo[2,3-b]pyridine-3-carboxylate, (2-(Chloromethyl)-4-(dibenzylamino)phenyl)methanol hydrochloride, (2R)-5-[Bis(phenylmethyl)amino]-1′-(1,1-dimethylethyl)-1,3-dihydrospiro[2H-indene-2,3′-[3H]pyrrolo[2,3-b]pyridin]-2′(1′H)-on, 1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-9-hydroxy-(9R)-cinchonanium bromide, Cinchonidine DerivativeSpirocyclization
Desymmetrization, (2α,6α)-tetrahydro-1-methyl-4-oxo-2,6-diphenyl-2H-Thiopyranium tetrafluoroborate(1-), (R,E)-5-(methylthio)-1,5-diphenylpent-1-en-3-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonidine DerivativeDesymmetrization
Friedel-Crafts reaction, isatins, 1-naphthols, 3-aryl-3-hydroxy-2-oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Friedel-Crafts reaction, 1-Benzyl-5-bromoisatin, 3-Methoxyphenol, (3R)-5-Bromo-1,3-dihydro-3-hydroxy-3-(2-hydroxy-4-methoxyphenyl)-1-(phenylmethyl)-2H-indol-2-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(8α,9S)-cinchonan-9-ylthiourea, Cinchonidine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Trifluoromethylthiolation, methyl 7-bromo-1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate, Trichloroisocyanuric Acid, Trifluoromethanethiol silver salt, methyl (S)-7-bromo-1-oxo-2-((trifluoromethyl)thio)-1,2,3,4-tetrahydronaphthalene-2-carboxylate, 3-[(8α,9S)-Cinchonan-9-ylamino]-4-[[4-(trifluoromethyl)phenyl]amino]-3-cyclobutene-1,2-dione, Cinchonidine DerivativeFluorination, Fluoromethylation, Trifluoromethylthiolation
