Tandem conjugate addition – intramolecular cyclization, 1,4-dien-3-ones, ethyl 2-cyanoacetate or malonitrile, 2-amino-4H-pyrans, Quinine BaseCyclization, Further Cyclizations, Intramolecular cyclization, Tandem conjugate Addition Cyclization, substituted ortho-quinone methides, malononitrile, 6-amino-8-substituted-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile, Quinine BaseCyclization Synthesis of 2,2´-Binaphthol-Type Biaryls, substituted benzoquinone, substituted naphthalen-2-ol, substituted (R)-2-(2-hydroxynaphthalen-1-yl)benzene-1,4-diol, Quinine BaseAtropisomer synthesis Spirocyclization Michael/Michael domino, substituted 5-methyl-4-((4-oxo-4H-chromen-3-yl)methyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, substituted tert-butyl (E)-2-(1-acetyl-2-oxoindolin-3-ylidene)acetate or substituted tert-butyl (E)-2-(2-oxobenzofuran-3(2H)-ylidene)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Phospha-Michael Addition, 3-substituted cyclohex-2-en-1-one, diphenylphosphine oxide, 3-substituted-3-(diphenylphosphoryl)cyclohexan-1-one, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Phospha-Michael Addition Vinylogous Michael Addition, alpha,beta unsaturated ketones, pyrroles, substituted 1,5-dihydro-2H-pyrrol-2-ones, benzoic acid, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Vinylogous Michael Addition Aza-Michael Addition, methylhydrazine, 4-(tert-butyl)benzaldehyde, (E)-chalcone, (R)-1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole, 3,5-Dichloro-N-(8α,9S)-cinchonan-9-ylbenzamide, Cinchonidine DerivativeAza-Michael, Michael Addition Aza-Michael Addition, (E)-3-(2-(2-oxopropyl)phenyl)-1-phenylprop-2-en-1-one, 4-methylbenzenesulfonamide, (R)-1-phenyl-2-(2-tosyl-1,2-dihydroisoquinolin-1-yl)ethan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Michael Addition Spirocyclization Mannich – Boc-Deprotection – Aza-Michael, tert-butyl (Z)-(2-oxoindolin-3-ylidene)carbamate, ethyl (E)-4-(2-oxoindolin-3-yl)but-2-enoate, 3,3′-pyrrolidinyl-dispirooxindoles, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCascade reaction, Spirocyclization Cascade Aza-Michael-Aldol reaction, 2-(1H-pyrrol-2-yl)-2-oxoacetates, enones, chiral pyrrolizines, (8α,9S)-6′-(2,2-Dimethylpropoxy)cinchonan-9-amine, Quinine DerivativeCascade reaction, Cyclization« Older EntriesNext Entries »
Tandem conjugate addition – intramolecular cyclization, 1,4-dien-3-ones, ethyl 2-cyanoacetate or malonitrile, 2-amino-4H-pyrans, Quinine BaseCyclization, Further Cyclizations, Intramolecular cyclization, Tandem conjugate Addition
Cyclization, substituted ortho-quinone methides, malononitrile, 6-amino-8-substituted-8H-[1,3]dioxolo[4,5-g]chromene-7-carbonitrile, Quinine BaseCyclization
Synthesis of 2,2´-Binaphthol-Type Biaryls, substituted benzoquinone, substituted naphthalen-2-ol, substituted (R)-2-(2-hydroxynaphthalen-1-yl)benzene-1,4-diol, Quinine BaseAtropisomer synthesis
Spirocyclization Michael/Michael domino, substituted 5-methyl-4-((4-oxo-4H-chromen-3-yl)methyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one, substituted tert-butyl (E)-2-(1-acetyl-2-oxoindolin-3-ylidene)acetate or substituted tert-butyl (E)-2-(2-oxobenzofuran-3(2H)-ylidene)acetate, N-[3,5-Bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Phospha-Michael Addition, 3-substituted cyclohex-2-en-1-one, diphenylphosphine oxide, 3-substituted-3-(diphenylphosphoryl)cyclohexan-1-one, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)- 6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Phospha-Michael Addition
Vinylogous Michael Addition, alpha,beta unsaturated ketones, pyrroles, substituted 1,5-dihydro-2H-pyrrol-2-ones, benzoic acid, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael Addition, Vinylogous Michael Addition
Aza-Michael Addition, methylhydrazine, 4-(tert-butyl)benzaldehyde, (E)-chalcone, (R)-1-methyl-3,5-diphenyl-4,5-dihydro-1H-pyrazole, 3,5-Dichloro-N-(8α,9S)-cinchonan-9-ylbenzamide, Cinchonidine DerivativeAza-Michael, Michael Addition
Aza-Michael Addition, (E)-3-(2-(2-oxopropyl)phenyl)-1-phenylprop-2-en-1-one, 4-methylbenzenesulfonamide, (R)-1-phenyl-2-(2-tosyl-1,2-dihydroisoquinolin-1-yl)ethan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeAza-Michael, Michael Addition
Spirocyclization Mannich – Boc-Deprotection – Aza-Michael, tert-butyl (Z)-(2-oxoindolin-3-ylidene)carbamate, ethyl (E)-4-(2-oxoindolin-3-yl)but-2-enoate, 3,3′-pyrrolidinyl-dispirooxindoles, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeCascade reaction, Spirocyclization
Cascade Aza-Michael-Aldol reaction, 2-(1H-pyrrol-2-yl)-2-oxoacetates, enones, chiral pyrrolizines, (8α,9S)-6′-(2,2-Dimethylpropoxy)cinchonan-9-amine, Quinine DerivativeCascade reaction, Cyclization
