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Cyclization, ketimines, alpha-isocyanoacetonitriles, 4,5,5-trisubstituted 1-(diphenylphosphoryl)-4,5-dihydro-1H-imidazole-4-carbonitrile, copper(II) triflate, N-(9R)-Cinchonan-9-yl-2-pyridinecarboxamide, Cinchonine Derivative

Cyclization, Cyclization, Further Cyclizations

Kinetic Resolution, 2‐sulfonylalkyl phenols, allenic esters, ethyl (S,E)-3-(2-(phenyl(tosyl)methyl)phenoxy)but-2-enoate, (3α,9S)-3,9-epoxy-10,11-dihydro-cinchonan, Dihydrochinchonine Derivative

Alkylation, Allylation, Dynamic Kinetic Resolution, Resolution

Dearomatization, substituted 1-((2-((1H-indol-3-yl)methyl)phenyl)ethynyl)naphthalen-2-ol, substituted (5aR,10aR)-10,10a-dihydro-5H-benzo[5,6]naphtho[2′,3′:3,4]chromeno[2,3-b]indole, N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea, Cinchonine Derivative

Cyclization, Dearomatization, Further Cyclizations, Further reactions, Intramolecular cyclization, Spirocyclization

intramolecular Oxa-Michael, (E)-2-(3-oxo-3-phenylprop-1-en-1-yl)benzaldehyde, (R)-2-(1,3-dihydroisobenzofuran-1-yl)-1-phenylethan-1-one, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative

Michael Addition, Oxa-Michael Addition

Friedel-Crafts reaction, indoles, alkyl trifluoropyruvate, substituted (S)-3,3,3-trifluoro-2-hydroxy-2-(1H-indol-3-yl)propanoate, 3,3′,3′′-[1,3,5-benzenetriyltris(methyleneimino)]tris[4-[(9R)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione, Cinchonine Derivative

Friedel-Crafts, Friedel-Crafts reaction

Michael Addition, cyclohex-2-en-1-one, diisopropyl malonate, diisopropyl (R)-2-(3-oxocyclohexyl)malonate, N-[(1R,2R)-2-Aminocyclohexyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Michael, Michael Addition

Mannich reaction, benzoylacetic acid, tert-butyl (E)-(1-benzyl-2-oxoindolin-3-ylidene)carbamate, tert-butyl (S)-(1-benzyl-2-oxo-3-(2-oxo-2-phenylethyl)indolin-3-yl)carbamate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Mannich, Mannich

Bromoaminocyclization, (E)-substituted N-(but-3-en-1-yl)-4-nitrobenzenesulfonamide, 2-bromoisoindoline-1,3-dione, 2-substituted (2S,3R)-3-bromo-1-((4-nitrophenyl)sulfonyl)pyrrolidine, (9S)-9-[N-(2,6-diethoxyphenyl)carbamothioate]-cinchonan-9-ol, Cinchonine Derivative

Bromination, Cyclization, Cyclization, Cycloaddition, Further Cyclizations, Intramolecular cyclization

Cyclization, functionalized chalcones, malononitrile, 2-amino-3-nitrile-chromenes, 1-naphthol, Quinine Base

Cyclization, Cycloaddition

Bromolactonization, 4-substituted pent-4-enoic acid, N-bromosuccinimide, 5-substituted (R)-5-(bromomethyl)-dihydrofuran-2(3H)-one, (9S)-9-[N-(2,4-dimethoxyphenyl)carbamothioate]-cinchonan-9-ol, Cinchonine Derivative

Bromination, Cyclization, Further Cyclizations, Intramolecular cyclization, Lactonization

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