Michael Addition, alpha,beta-enone, nitromethane, (R)-baclofen, (9R)-1-(9-anthracenylmethyl)-10,11-dihydro-9-(phenylmethoxy)-cinchonanium bromide, Dihydrocinchonine DerivativeMichael, Michael Addition Alkylation, substituted (Z)-4-chlorobut-3-en-2-one, alpha-substituted-alpha-cyanoacetates, substituted tert-butyl (R,Z)-2-cyano-5-oxohex-3-enoate, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium dibromide, Dihydrocinchonine DerivativeAlkylation, Alkylation Oxotrifluoromethylation, 1,3-substituted but-3-enal oxime, 3,3-dimethyl-1-(trifluoromethyl)-1,3-dihydro-1l3-benzo[d][1,2]iodaoxole, cyclic alkenyl oximes, copper acetate, N-[(9R)-10,11-dihydrocinchonan-9-yl]-2,3,4,5,6-pentamethyl-benzenesulfonamide, Dihydrocinchonine DerivativeCyclization, Fluorination, Fluoromethylation, Trifluoromethylation Alkynylation, cyclic beta-ketoesters, allyl 3-bromopropiolate, tert-butyl (S)-2-(3-(allyloxy)-3-oxoprop-1-yn-1-yl)-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (9S)-1-(9-anthracenylmethyl)-10,11-dihydro-9-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)oxy]-cinchonanium chloride, Dihydrocinchonine DerivativeAlkynylation Resolution of BINOLs, BINOLs, phenyl tosylate, (R)-BINOLs, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(quinolin-4-yl)methyl)-1-(2,3,4-trifluorobenzyl)quinuclidin-1-ium bromide, Dihydrocinchonine DerivativeAtropisomer synthesis, Kinetic resolution, Resolution Cycloaddition, aminoalkanoates, alkenes, azomethine Ylides, silver carbonate, (R)-binol-phosphoric acid, Dihydrocinchonine Base1,3-Dipolar Cycloaddition, Cycloaddition NH-Insertion, ethyl 2-diazo-2-phenylacetate, arylamines, N-substituted ethyl 2-amino-2-phenylacetate, Dihydrocinchonine BaseAmination Spirocyclization, N-substituted 1-(2-hydroxy-1H-indol-3-yl)ethan-1-one, alpha,beta-unsaturated methylketones, six-membered spirocyclic oxindoles, (9R)-cinchonan-9-amine, Cinchonine DerivativeAldol, Aldol, Cascade reaction, Michael, Michael Addition, Spirocyclization Nitro-Mannich, phosphorylated ketimines, nitromethane, tetrasubstituted alpha-aminophosphonates, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9S)-cinchonan-9-ylthiourea, Cinchonine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich Decarboxylative Mannich reaction, tert-butyl (Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)carbamate, 3-(4-fluorophenyl)-3-oxopropanoic acid, tert-butyl (S)-(4-(2-(4-fluorophenyl)-2-oxoethyl)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)carbamate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich« Older EntriesNext Entries »
Michael Addition, alpha,beta-enone, nitromethane, (R)-baclofen, (9R)-1-(9-anthracenylmethyl)-10,11-dihydro-9-(phenylmethoxy)-cinchonanium bromide, Dihydrocinchonine DerivativeMichael, Michael Addition
Alkylation, substituted (Z)-4-chlorobut-3-en-2-one, alpha-substituted-alpha-cyanoacetates, substituted tert-butyl (R,Z)-2-cyano-5-oxohex-3-enoate, (9S)-(9′′S)-1,1′′-[1,3-phenylenebis(methylene)]bis[10,11-dihydro-9-(2-propen-1-yloxy)-cinchonanium dibromide, Dihydrocinchonine DerivativeAlkylation, Alkylation
Oxotrifluoromethylation, 1,3-substituted but-3-enal oxime, 3,3-dimethyl-1-(trifluoromethyl)-1,3-dihydro-1l3-benzo[d][1,2]iodaoxole, cyclic alkenyl oximes, copper acetate, N-[(9R)-10,11-dihydrocinchonan-9-yl]-2,3,4,5,6-pentamethyl-benzenesulfonamide, Dihydrocinchonine DerivativeCyclization, Fluorination, Fluoromethylation, Trifluoromethylation
Alkynylation, cyclic beta-ketoesters, allyl 3-bromopropiolate, tert-butyl (S)-2-(3-(allyloxy)-3-oxoprop-1-yn-1-yl)-1-oxo-2,3-dihydro-1H-indene-2-carboxylate, (9S)-1-(9-anthracenylmethyl)-10,11-dihydro-9-[(tricyclo[3.3.1.13,7]dec-1-ylcarbonyl)oxy]-cinchonanium chloride, Dihydrocinchonine DerivativeAlkynylation
Resolution of BINOLs, BINOLs, phenyl tosylate, (R)-BINOLs, (1S,2R,4S,5R)-5-ethyl-2-((S)-hydroxy(quinolin-4-yl)methyl)-1-(2,3,4-trifluorobenzyl)quinuclidin-1-ium bromide, Dihydrocinchonine DerivativeAtropisomer synthesis, Kinetic resolution, Resolution
Cycloaddition, aminoalkanoates, alkenes, azomethine Ylides, silver carbonate, (R)-binol-phosphoric acid, Dihydrocinchonine Base1,3-Dipolar Cycloaddition, Cycloaddition
NH-Insertion, ethyl 2-diazo-2-phenylacetate, arylamines, N-substituted ethyl 2-amino-2-phenylacetate, Dihydrocinchonine BaseAmination
Spirocyclization, N-substituted 1-(2-hydroxy-1H-indol-3-yl)ethan-1-one, alpha,beta-unsaturated methylketones, six-membered spirocyclic oxindoles, (9R)-cinchonan-9-amine, Cinchonine DerivativeAldol, Aldol, Cascade reaction, Michael, Michael Addition, Spirocyclization
Nitro-Mannich, phosphorylated ketimines, nitromethane, tetrasubstituted alpha-aminophosphonates, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-(9S)-cinchonan-9-ylthiourea, Cinchonine DerivativeAza-Henry, Henry, Mannich, Nitro-Mannich
Decarboxylative Mannich reaction, tert-butyl (Z)-(3-methyl-5-oxo-1-phenyl-1,5-dihydro-4H-pyrazol-4-ylidene)carbamate, 3-(4-fluorophenyl)-3-oxopropanoic acid, tert-butyl (S)-(4-(2-(4-fluorophenyl)-2-oxoethyl)-3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-yl)carbamate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeMannich, Mannich
