Michael Addition, β-nitrostyrenes, acetylacetone, substituted 3-nitroethyl-2,4-pentanedione, (9S)-(9′′S)-1,1′′-[[5,11,17,23-tetrakis(1,1-dimethylethyl)-26,28-dihydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl]bis(oxy-3,1-propanediyl)]bis[9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition Spirocyclization, 3-hydroxyoxindoles, 3-fluoroethylidene oxindoles, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((3’S,4R)-3′-chlorospiro[benzo[d][1,3]oxazine-4,2′-indolin]-1′-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((2R,3S)-3-chloro-2′-phenyl-4’H-spiro[indoline-2,5′-oxazol]-1-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization Desymmetrization, C2-symmetric derivatives, 5-substituted cyclohexane-1,3-dione, decalin derivatives, (9S)-10,11-Dihydro-6′-methoxy-9-(9-phenanthrenyloxy)cinchonan, Dihydroquinidine DerivativeDesymmetrization Selenolactonization, 4-(4-fluorophenyl)pent-4-enoic acid, N-(Phenylseleno)phthalimide, (R)-5-(4-fluorophenyl)-5-((phenylselanyl)methyl)dihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Lactonization, Selenenylation Iodination, substituted 2-(prop-2-yn-1-yl)pent-4-ynoic acid, N-iodosuccinimide, highly substituted enol lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeDesymmetrization, Iodination, Lactonization Spirocyclization, benzofurans, N-chlorophthalimide, substituted (2R,3S)-3-chloro-3H,4’H-spiro[benzofuran-2,5′-oxazole], 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Dearomatization, Spirocyclization Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, 5‐alkenyl thiazolones, pyrrolidinyl spirooxindoles, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations« Older EntriesNext Entries »
Michael Addition, β-nitrostyrenes, acetylacetone, substituted 3-nitroethyl-2,4-pentanedione, (9S)-(9′′S)-1,1′′-[[5,11,17,23-tetrakis(1,1-dimethylethyl)-26,28-dihydroxypentacyclo[19.3.1.13,7.19,13.115,19]octacosa-1(25),3,5,7(28),9,11,13(27),15,17,19(26),21,23-dodecaene-25,27-diyl]bis(oxy-3,1-propanediyl)]bis[9-hydroxy-cinchonanium bromide, Cinchonidine DerivativeMichael, Michael Addition
Spirocyclization, 3-hydroxyoxindoles, 3-fluoroethylidene oxindoles, spirooxindoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(9R)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-cyclobutene-1,2-dione, Dihydroquinidine DerivativeCascade reaction, Spirocyclization
Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((3’S,4R)-3′-chlorospiro[benzo[d][1,3]oxazine-4,2′-indolin]-1′-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization
Chlorination, indole derived benzamides, 1,3-Dichloro-5,5-diphenyl-2,4-imidazolidinedione, substituted 1-((2R,3S)-3-chloro-2′-phenyl-4’H-spiro[indoline-2,5′-oxazol]-1-yl)ethan-1-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Spirocyclization
Desymmetrization, C2-symmetric derivatives, 5-substituted cyclohexane-1,3-dione, decalin derivatives, (9S)-10,11-Dihydro-6′-methoxy-9-(9-phenanthrenyloxy)cinchonan, Dihydroquinidine DerivativeDesymmetrization
Selenolactonization, 4-(4-fluorophenyl)pent-4-enoic acid, N-(Phenylseleno)phthalimide, (R)-5-(4-fluorophenyl)-5-((phenylselanyl)methyl)dihydrofuran-2(3H)-one, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeFurther reactions, Lactonization, Selenenylation
Iodination, substituted 2-(prop-2-yn-1-yl)pent-4-ynoic acid, N-iodosuccinimide, highly substituted enol lactones, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeDesymmetrization, Iodination, Lactonization
Spirocyclization, benzofurans, N-chlorophthalimide, substituted (2R,3S)-3-chloro-3H,4’H-spiro[benzofuran-2,5′-oxazole], 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Dearomatization, Spirocyclization
Spirocyclization, substituted (E)-3-((2,2,2-trifluoroethyl)imino)indolin-2-one, 5‐alkenyl thiazolones, pyrrolidinyl spirooxindoles, (9S,9′′S)-9,9′′-[(2,5-diphenyl-4,6-pyrimidinediyl)bis(oxy)]bis[10,11-dihydro-6′-methoxy-cinchonan], Dihydroquinidine DerivativeSpirocyclization
Chlorocyclization, alkeneamides, 1,3-dichloro-5,5-diphenylhydantoin, (5S,6R)-5-chloro-2,6-diphenyl-5,6-dihydro-4H-1,3-oxazine, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine, Dihydroquinidine DerivativeChlorination, Cyclization, Cyclization, Further Cyclizations
