Asymmetric Organocatalysis in the Remote (3 + 2)-Cycloaddition to 4-(Alk-1-en-1-yl)-3-cyanocoumarins.

DOI Number:

10.1021/acs.orglett.3c01189

Reaction Category:

MOP ID:

MOP_0000715

Educt:

(E)-2-oxo-4-styryl-2H-chromene-3-carbonitrile, diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate

Product:

diethyl (3R,4R,5S)-4-(3-cyano-2-oxo-2H-chromen-4-yl)-5-(2-hydroxyphenyl)-3-phenylpyrrolidine-2,2-dicarboxylate

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0