Friedel-crafts, 2-Methoxy-6-[[(4-methylphenyl)sulfonyl]phenylmethyl]phenol, 7-Hydroxyindole, (R)-6-((2-hydroxy-3-methoxyphenyl)(phenyl)methyl)-1H-indol-7-ol, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFriedel-Crafts, Friedel-Crafts reaction Aldol reaction, S-substituted 2-chloro-3-mercapto-3-oxopropanoic acid, aldehydes, (3S)-substituted (2S)-2-chloro-3-hydroxypropanethioesters, N-[[[(9R)-6′-methoxycinchonan-9-yl]amino]carbonyl]-4-methyl-benzenesulfonamide, Quinidine DerivativeAldol, Aldol Sulfur dioxide insertion, 1-alkynylnaphthalen-2-ols, potassium alkyltrifluoroborates, potassium metabisulfite, (S,E)-1-(1-(alkylsulfonyl)-2-vinyl)naphthalen-2-ols, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Further reactions, Sulfur dioxide insertion Chiral Peptide synthesis, amino acid methyl esters, racemic N-protected amino acids, peptides, (9S)-1,1′-bis(4,6-dimethoxy-1,3,5-triazin-2-yl)-9-hydroxy-6′-methoxy-cinchonanium tetrafluoroborate, Quinidine DerivativeAcylation, Further reactions, Peptide synthesis Aminohydroxylation, 1-(benzyloxy)-3-methoxy-2-methyl-5-vinylbenzene, N-chloro-N-sodio benzyl carbamate, benzyl (S)-(1-(3-(benzyloxy)-5-methoxy-4-methylphenyl)-2-hydroxyethyl)carbamate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions Michael Addition, (E)-4-(furan-2-yl)-4-oxobut-2-enenitrile, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (S)-2-((S)-1-cyano-3-(furan-2-yl)-3-oxopropyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition Desymmetrization, bis(enones), cyclohexene derivatives, 2-mercapto-5-bromophenol, (8α,9R)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeDesymmetrization Addition, 2-sulfonylalkyl phenols, nitriles, 2-amino-4H-chromenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization Diels Alder reaction, β-substituted cyclic enones, polyconjugated malononitriles, substituted (1R,3S,4R)-5-oxo-3-vinylbicyclo[2.2.2]octane-2,2-dicarbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction Alkylation, cyclic ketones, 2-methylbenzothiazolium iodide, 4-substituted 2-(3-methyl-2,3-dihydrobenzo[d]thiazol-2-yl)cyclohexan-1-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAlkylation, alpha-Alkylation« Older EntriesNext Entries »
Friedel-crafts, 2-Methoxy-6-[[(4-methylphenyl)sulfonyl]phenylmethyl]phenol, 7-Hydroxyindole, (R)-6-((2-hydroxy-3-methoxyphenyl)(phenyl)methyl)-1H-indol-7-ol, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeFriedel-Crafts, Friedel-Crafts reaction
Aldol reaction, S-substituted 2-chloro-3-mercapto-3-oxopropanoic acid, aldehydes, (3S)-substituted (2S)-2-chloro-3-hydroxypropanethioesters, N-[[[(9R)-6′-methoxycinchonan-9-yl]amino]carbonyl]-4-methyl-benzenesulfonamide, Quinidine DerivativeAldol, Aldol
Sulfur dioxide insertion, 1-alkynylnaphthalen-2-ols, potassium alkyltrifluoroborates, potassium metabisulfite, (S,E)-1-(1-(alkylsulfonyl)-2-vinyl)naphthalen-2-ols, 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Dihydroquinine DerivativeAtropisomer synthesis, Further reactions, Sulfur dioxide insertion
Chiral Peptide synthesis, amino acid methyl esters, racemic N-protected amino acids, peptides, (9S)-1,1′-bis(4,6-dimethoxy-1,3,5-triazin-2-yl)-9-hydroxy-6′-methoxy-cinchonanium tetrafluoroborate, Quinidine DerivativeAcylation, Further reactions, Peptide synthesis
Aminohydroxylation, 1-(benzyloxy)-3-methoxy-2-methyl-5-vinylbenzene, N-chloro-N-sodio benzyl carbamate, benzyl (S)-(1-(3-(benzyloxy)-5-methoxy-4-methylphenyl)-2-hydroxyethyl)carbamate, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis(oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine DerivativeAminohydroxylation, Further reactions
Michael Addition, (E)-4-(furan-2-yl)-4-oxobut-2-enenitrile, tert-butyl 2-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, tert-butyl (S)-2-((S)-1-cyano-3-(furan-2-yl)-3-oxopropyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate, N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea, Dihydroquinine DerivativeMichael, Michael Addition
Desymmetrization, bis(enones), cyclohexene derivatives, 2-mercapto-5-bromophenol, (8α,9R)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-10,11-dihydro-9-hydroxy-6′-methoxy-Cinchonanium bromide, Dihydroquinine DerivativeDesymmetrization
Addition, 2-sulfonylalkyl phenols, nitriles, 2-amino-4H-chromenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAddition, Cyclization
Diels Alder reaction, β-substituted cyclic enones, polyconjugated malononitriles, substituted (1R,3S,4R)-5-oxo-3-vinylbicyclo[2.2.2]octane-2,2-dicarbonitrile, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine Derivative[4+2]-Cycloaddition, Cycloaddition, Diels-Alder reaction
Alkylation, cyclic ketones, 2-methylbenzothiazolium iodide, 4-substituted 2-(3-methyl-2,3-dihydrobenzo[d]thiazol-2-yl)cyclohexan-1-one, (9R)-6′-methoxy-cinchonan-9-amine, Quinidine DerivativeAlkylation, alpha-Alkylation
