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Friedel-Crafts reaction, ethyl (E)-4-oxopent-2-enoate, 1H-indole, ethyl (R)-2-(1H-indol-3-yl)-4-oxopentanoate, (8α,9S)-10,11-dihydro-6′-methoxy-Cinchonan-9-amine (αS)-α-[[(1,1-dimethylethoxy)carbonyl]amino]benzeneacetate (1:2), Dihydroquinine Derivative

Friedel-Crafts, Friedel-Crafts reaction

Isomerization, trifluoromethyl imines, trifluoromethyl imines, (9S)-9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-6′-hydroxy-cinchonanium inner salt, Cupreidine Derivative

Isomerization

Desymmetrization, diolefinic diols, N-bromophthalimide, substituted ((3R,5S)-3-allyl-5-(bromomethyl)-tetrahydrofuran-3-yl)methanol, (9S)-9-[N-(4-ethoxyphenyl)carbamothioate]-6′-butoxy-cinchonan-9-ol, Cupreidine Derivative

Cyclization, Cyclization, Desymmetrization, Further Cyclizations

Michael Addition, 1,3-substituted (E)-4,4,4-trifluorobut-2-en-1-one, nitromethane, 1,3-substituted (S)-4,4,4-trifluoro-3-(nitromethyl)-butan-1-one, (9S)-1-[[3,5-bis(1,1-dimethylethyl)phenyl]methyl]-9-butoxy-6′-hydroxy-cinchonanium bromide, Cupreidine Derivative

Michael, Michael Addition

Amination, α-substituted α-cyanoacetates, disubstituted (E)-diazene-1,2-dicarboxylate, substituted 1-(1-cyano-2-ethoxy-2-oxoethyl)hydrazine-1,2-dicarboxylate, (8α,9R)-9-(Phenylmethoxy)-cinchonan-6′-ol, Cupreine Derivative

alpha-Amination, Amination

Amination, α-substituted α-cyanoacetates, disubstituted (E)-diazene-1,2-dicarboxylate, substituted 1-(1-cyano-2-ethoxy-2-oxoethyl)hydrazine-1,2-dicarboxylate, (9S)-9-(phenylmethoxy)-cinchonan-6′-ol, Cupreidine Derivative

alpha-Amination, Amination

Cycloaddition, cyclic enones, azomethine imines, 9-substituted (4aR,8aR)-octahydro-3H,8H-pyrazolo[1,2-a]indazole-3,8-dione, (9R)-9-Aminocinchonan-6′-ol, Cupreidine Derivative

1,3-Dipolar Cycloaddition, Cycloaddition

Cycloaddition, diazo compounds, isoquinolinium methylides, [1,2,4] triazino [5,4-a] isoquinoline derivatives, (1S,2R,4S,5R)-2-((S)-(hexyloxy)(6-hydroxyquinolin-4-yl)methyl)-1-(2-methylbenzyl)-5-vinylquinuclidin-1-ium bromide, Cupreidine Derivative

[3+3]-Cycloaddition, Cycloaddition

Fluorination, N-(2-(5-mesityl-1-methyl-1H-indol-3-yl)ethyl)acetamide, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide, 1-((3aR,8aS)-3a-fluoro-5-mesityl-8-methyl-3,3a,8,8a-tetrahydropyrrolo[2,3-b]indol-1(2H)-yl)ethan-1-one, (8α,9R)-(8′′α,9′′R)-9,9′′-[1,4-Phthalazinediylbis (oxy)]bis[10,11-dihydro-6′-methoxycinchonan], Dihydroquinine Derivative

Fluorination, Fluorocyclization

Conjugate Addition of phosphonates, (E)-1-(4-methoxyphenyl)but-2-en-1-one, diphenyl phosphonate, diphenyl (S)-(4-(4-methoxyphenyl)-4-oxobutan-2-yl)phosphonate, 2-[[[[3,5-Bis(1,1-dimethylethyl)phenyl]methyl]amino][[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]amino]methylene]-Propanedinitrile, Dihydroquinine Derivative

Conjugate addition of phosphonates, Further reactions

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