Michael Addition, ethyl (Z)-3-nitro-2-(p-tolyl)acrylate, 5-isobutylfuran-2(3H)-one, ethyl (R)-2-((R)-2-isobutyl-5-oxo-2,5-dihydrofuran-2-yl)-3-nitro-2-(p-tolyl)propanoate, (8α,9S)-9-[[2,4,6-Tris(1-methylethyl)phenyl]methoxy]cinchonan-6′-ol, Cupreine DerivativeMichael, Michael Addition Michael Addition, α-aryl-α-isocyanoacetates, (Ethenylselenonyl)benzene, α,α-disubstituted α-amino acids, (8α,9R)-9-Butoxycinchonan-6′-ol, Cupreine DerivativeMichael, Michael Addition Spirocyclization, isatin-derived β,γ-unsaturated α-ketoesters, substituted 3-hydroxy-4H-chromen-4-one, spirocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization Cacade reaction, 1,1-Dimethylethyl 2,3-dihydro-1-oxo-1H-indene-2-carboxylates, (Ethenylselenonyl)benzene, (2′S)-4,5-Dihydrospiro[furan-3(2H),2′-[2H]indene]-1′,2(3′H)-diones, (8α,9R)-9-(1-Phenanthrenyloxy)cinchonan-6′-ol, Cupreine DerivativeCascade reaction, Michael Addition, Spirocyclization gamma-Alkylation, alpha,beta unsaturated aldehydes, bis(4-(dimethylamino)phenyl)methanol, gamma-alkylated alpha,beta unsaturated aldehydes, 2-[[(8α,9S)-9-Aminocinchonan-6′-yl]oxy]acetic acid, Cupreine DerivativeAlkylation, gamma-Alkylation Cyclization, (E)-6-hydroxy-1-substituted-hex-2-en-1-one, (R)-1-substituted-2-(tetrahydrofuran-2-yl)ethan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization Spirocyclization, substituted indolin-2-one, substituted indoline-2,3-dione, spirooxindole δ‐lactones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization Amination, 1,2,3,4-tetrahydro-1-oxo-N-phenyl-2-naphthalenecarbothioamide, diisopropyl azodicarboxylate, diisopropyl (R,Z)-1-oxo-5′-(phenylimino)-3,4-dihydro-1H-spiro[naphthalene-2,4′-[1,2,3]thiadiazolidine]-2′,3′-dicarboxylate, Cupreine BaseAmination, Spirocyclization Friedel-Crafts reaction, isatins, indoles, 3-Indolyl-3-hydroxy-2-oxindoles, Cupreine BaseFriedel-Crafts, Friedel-Crafts reaction Aldol reaction, N-benzyl isatins, rifluoromethyl α-fluorinated gem-diols, 3-hydroxy oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Aldol« Older Entries
Michael Addition, ethyl (Z)-3-nitro-2-(p-tolyl)acrylate, 5-isobutylfuran-2(3H)-one, ethyl (R)-2-((R)-2-isobutyl-5-oxo-2,5-dihydrofuran-2-yl)-3-nitro-2-(p-tolyl)propanoate, (8α,9S)-9-[[2,4,6-Tris(1-methylethyl)phenyl]methoxy]cinchonan-6′-ol, Cupreine DerivativeMichael, Michael Addition
Michael Addition, α-aryl-α-isocyanoacetates, (Ethenylselenonyl)benzene, α,α-disubstituted α-amino acids, (8α,9R)-9-Butoxycinchonan-6′-ol, Cupreine DerivativeMichael, Michael Addition
Spirocyclization, isatin-derived β,γ-unsaturated α-ketoesters, substituted 3-hydroxy-4H-chromen-4-one, spirocycles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMichael, Michael Addition, Spirocyclization
Cacade reaction, 1,1-Dimethylethyl 2,3-dihydro-1-oxo-1H-indene-2-carboxylates, (Ethenylselenonyl)benzene, (2′S)-4,5-Dihydrospiro[furan-3(2H),2′-[2H]indene]-1′,2(3′H)-diones, (8α,9R)-9-(1-Phenanthrenyloxy)cinchonan-6′-ol, Cupreine DerivativeCascade reaction, Michael Addition, Spirocyclization
gamma-Alkylation, alpha,beta unsaturated aldehydes, bis(4-(dimethylamino)phenyl)methanol, gamma-alkylated alpha,beta unsaturated aldehydes, 2-[[(8α,9S)-9-Aminocinchonan-6′-yl]oxy]acetic acid, Cupreine DerivativeAlkylation, gamma-Alkylation
Cyclization, (E)-6-hydroxy-1-substituted-hex-2-en-1-one, (R)-1-substituted-2-(tetrahydrofuran-2-yl)ethan-1-one, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Further Cyclizations, Intramolecular cyclization
Spirocyclization, substituted indolin-2-one, substituted indoline-2,3-dione, spirooxindole δ‐lactones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization
Amination, 1,2,3,4-tetrahydro-1-oxo-N-phenyl-2-naphthalenecarbothioamide, diisopropyl azodicarboxylate, diisopropyl (R,Z)-1-oxo-5′-(phenylimino)-3,4-dihydro-1H-spiro[naphthalene-2,4′-[1,2,3]thiadiazolidine]-2′,3′-dicarboxylate, Cupreine BaseAmination, Spirocyclization
Friedel-Crafts reaction, isatins, indoles, 3-Indolyl-3-hydroxy-2-oxindoles, Cupreine BaseFriedel-Crafts, Friedel-Crafts reaction
Aldol reaction, N-benzyl isatins, rifluoromethyl α-fluorinated gem-diols, 3-hydroxy oxindoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Aldol
