Spirocyclization, substituted 4-(2-hydroxybenzylidene)cyclohexa-2,5-dien-1-one, substituted 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carbaldehyde, spiro-3,4-dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization Spirocyclization, 3-alkylidene oxindoles, isatins, spirooxindole dihydropyranones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol Spirocyclization, N-alkoxy-4-oxo-acrylamides, isatin-derived ketimines, spirooxindole-imidazolidinones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization Cyclization, substituted 5-methylenethiazol-4(5H)-one, 2,4,4,4-tetrafluoro-3,3-dihydroxy-1-phenylbutan-1-one, pyran derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cyclization, Further Cyclizations Atropisomer Synthesis, substituted 1-ethynylnaphthalen-2-ol, tetrasubsituted phosphinothioic thioanhydride, phosphorodithiolated styrenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis Michael Addition, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, nitroalkenes, 4-substituted diethyl (3R,5R)-3-nitro-5-(trifluoromethyl)pyrrolidine-2,2-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael, Michael Addition Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol Cyclization, diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate, benzyl (E)-2-oxo-4-phenylbut-3-enoate, chromenopyrrolidines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations Cyclization, 2-formylbenzonitrile, diisopropyl malonate, 3-substituted isoindolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations« Older Entries
Spirocyclization, substituted 4-(2-hydroxybenzylidene)cyclohexa-2,5-dien-1-one, substituted 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carbaldehyde, spiro-3,4-dihydrocoumarins, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeSpirocyclization
Spirocyclization, 3-alkylidene oxindoles, isatins, spirooxindole dihydropyranones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol
Spirocyclization, N-alkoxy-4-oxo-acrylamides, isatin-derived ketimines, spirooxindole-imidazolidinones, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine Derivative[3+2]-Cycloaddition, Cycloaddition, Spirocyclization
Cyclization, substituted 5-methylenethiazol-4(5H)-one, 2,4,4,4-tetrafluoro-3,3-dihydroxy-1-phenylbutan-1-one, pyran derivatives, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
Atropisomer Synthesis, substituted 1-ethynylnaphthalen-2-ol, tetrasubsituted phosphinothioic thioanhydride, phosphorodithiolated styrenes, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAtropisomer synthesis
Michael Addition, diethyl 2-((2,2,2-trifluoroethyl)imino)malonate, nitroalkenes, 4-substituted diethyl (3R,5R)-3-nitro-5-(trifluoromethyl)pyrrolidine-2,2-dicarboxylate, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeCascade reaction, Michael, Michael Addition
Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, 3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol
Spirocyclization, 3-alkylidene oxindoles, isatins, spirocyclic indoles, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeAldol, Cascade reaction, Spirocyclization, Vinylogous Aldol
Cyclization, diethyl (E)-2-((2-hydroxybenzylidene)amino)malonate, benzyl (E)-2-oxo-4-phenylbut-3-enoate, chromenopyrrolidines, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
Cyclization, 2-formylbenzonitrile, diisopropyl malonate, 3-substituted isoindolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCyclization, Cyclization, Further Cyclizations
