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Alkylation, N-(Diphenylmethylene)glycine 1-methyl-1-phenylethyl ester, Benzyl bromide, N-(Diphenylmethylene)-L-phenylalanine 1-methyl-1-phenylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine Derivative

Alkylation, Alkylation

Michael Addition, 3-aryloxindoles, nitroenynes, quaternary oxindoles, Bis(1-methylethyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine Derivative

Michael, Michael Addition

Mannich reaction, 3-(2,4-dioxopentan-3-yl)-1,1-dimethylurea, benzyl ((1Z,2E)-3-phenylallylidene)carbamate, benzyl (R,E)-(4-acetyl-4-(3,3-dimethylureido)-5-oxo-1-phenylhex-1-en-3-yl)carbamate, Cinchonidine Base

Mannich, Mannich

Dynamic kinetic resolution, 2,2,2-triphenyl-N-(p-tolylsulfinyl)acetamide, 2,2-dimethylpropan-1-ol, [S(R)]-4-methyl-N-(2,2,2-triphenylacetyl)-Benzenesulfinimidic acid 2,2-dimethylpropyl ester, Cinchonidine Base

Dynamic Kinetic Resolution, Resolution

Tandem Michael-Knoevenagel, 2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction

Hydrophosphonylation, trifluoromethyl 2(1H)-quinazolinones, dimethyl phosphonate, 4,4-disubstituted 2(1H)-quinazolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Hydrophosphonylation

Mannich reaction, methyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate, tert-butyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, tetrasubstituted stereocenter containing 3-aminooxindole, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Mannich, Mannich

Phosphination, 1,2 disubstituted 2-diazoethan-1-one, disubstituted phosphine oxide, substituted (2-hydroxyethyl)phosphine oxide, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine Derivative

Further reactions, Phosphination

Amination, substituted 3-oxopropanamide, di-tert-butyl (E)-diazene-1,2-dicarboxylate, serines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivative

alpha-Amination, Amination

Spirocyclization, oxindoles, pyrazolones, bi-spirocyclic compounds, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine Derivative

Cascade reaction, Spirocyclization

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