Alkylation, N-(Diphenylmethylene)glycine 1-methyl-1-phenylethyl ester, Benzyl bromide, N-(Diphenylmethylene)-L-phenylalanine 1-methyl-1-phenylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation Michael Addition, 3-aryloxindoles, nitroenynes, quaternary oxindoles, Bis(1-methylethyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition Mannich reaction, 3-(2,4-dioxopentan-3-yl)-1,1-dimethylurea, benzyl ((1Z,2E)-3-phenylallylidene)carbamate, benzyl (R,E)-(4-acetyl-4-(3,3-dimethylureido)-5-oxo-1-phenylhex-1-en-3-yl)carbamate, Cinchonidine BaseMannich, Mannich Dynamic kinetic resolution, 2,2,2-triphenyl-N-(p-tolylsulfinyl)acetamide, 2,2-dimethylpropan-1-ol, [S(R)]-4-methyl-N-(2,2,2-triphenylacetyl)-Benzenesulfinimidic acid 2,2-dimethylpropyl ester, Cinchonidine BaseDynamic Kinetic Resolution, Resolution Tandem Michael-Knoevenagel, 2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction Hydrophosphonylation, trifluoromethyl 2(1H)-quinazolinones, dimethyl phosphonate, 4,4-disubstituted 2(1H)-quinazolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeHydrophosphonylation Mannich reaction, methyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate, tert-butyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, tetrasubstituted stereocenter containing 3-aminooxindole, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich Phosphination, 1,2 disubstituted 2-diazoethan-1-one, disubstituted phosphine oxide, substituted (2-hydroxyethyl)phosphine oxide, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeFurther reactions, Phosphination Amination, substituted 3-oxopropanamide, di-tert-butyl (E)-diazene-1,2-dicarboxylate, serines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivativealpha-Amination, Amination Spirocyclization, oxindoles, pyrazolones, bi-spirocyclic compounds, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization« Older Entries
Alkylation, N-(Diphenylmethylene)glycine 1-methyl-1-phenylethyl ester, Benzyl bromide, N-(Diphenylmethylene)-L-phenylalanine 1-methyl-1-phenylethyl ester, (8α,9R)-1-(9-anthracenylmethyl)-9-(2-propenyloxy)-Cinchonanium bromide, Cinchonidine DerivativeAlkylation, Alkylation
Michael Addition, 3-aryloxindoles, nitroenynes, quaternary oxindoles, Bis(1-methylethyl) N-(8α,9S)-cinchonan-9-ylphosphoramidate, Cinchonidine DerivativeMichael, Michael Addition
Mannich reaction, 3-(2,4-dioxopentan-3-yl)-1,1-dimethylurea, benzyl ((1Z,2E)-3-phenylallylidene)carbamate, benzyl (R,E)-(4-acetyl-4-(3,3-dimethylureido)-5-oxo-1-phenylhex-1-en-3-yl)carbamate, Cinchonidine BaseMannich, Mannich
Dynamic kinetic resolution, 2,2,2-triphenyl-N-(p-tolylsulfinyl)acetamide, 2,2-dimethylpropan-1-ol, [S(R)]-4-methyl-N-(2,2,2-triphenylacetyl)-Benzenesulfinimidic acid 2,2-dimethylpropyl ester, Cinchonidine BaseDynamic Kinetic Resolution, Resolution
Tandem Michael-Knoevenagel, 2-mercaptobenzaldehyde, diethyl 2-(2-methoxybenzylidene)malonate, substituted thiochromanes, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction
Hydrophosphonylation, trifluoromethyl 2(1H)-quinazolinones, dimethyl phosphonate, 4,4-disubstituted 2(1H)-quinazolinones, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeHydrophosphonylation
Mannich reaction, methyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate, tert-butyl (E)-(1-methyl-2-oxoindolin-3-ylidene)carbamate, tetrasubstituted stereocenter containing 3-aminooxindole, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeMannich, Mannich
Phosphination, 1,2 disubstituted 2-diazoethan-1-one, disubstituted phosphine oxide, substituted (2-hydroxyethyl)phosphine oxide, 3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4- [[(8α,9S)-6′-methoxycinchonan-9-yl]amino]- 3-Cyclobutene-1,2-dione, Quinine DerivativeFurther reactions, Phosphination
Amination, substituted 3-oxopropanamide, di-tert-butyl (E)-diazene-1,2-dicarboxylate, serines, (8α,9S)-6′-Methoxycinchonan-9-amine, Quinine Derivativealpha-Amination, Amination
Spirocyclization, oxindoles, pyrazolones, bi-spirocyclic compounds, N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea, Quinine DerivativeCascade reaction, Spirocyclization